Primary pulmonary spindle cell tumour (haemangiopericytoma) in a dog

Vignoli, Massimo; Buchholz, J.; Morandi, Federica; Laddaga, E.L.; Brunetti, Barbara; Rossi, Federica; Terragni, Rossella; Sarli, Giuseppe

doi:10.1111/j.1748-5827.2008.00610.x

Cited by 8 publications

(9 citation statements)

References 22 publications

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“…Heterogeneous enhancement would not be a valid specific criterion for this disease, as 64% of canine primary lung tumors also have heterogeneous contrast uptake after contrast medium injection . In addition, peripheral enhancement with absence of central contrast medium uptake does not preclude a neoplastic origin: a primary pulmonary haemangiopericytoma (spindle cell tumor) with only peripheral enhancement in a pseudocapsule has been described in a dog . These various findings in dogs differ from people, with absence of significant lung nodule enhancement (≤15 HU) on CT being strongly predictive of a benign lesion in human medicine .…”

Section: Discussioncontrasting

confidence: 60%

Computed Tomographic Characteristics of Eosinophilic Pulmonary Granulomatosis in Five Dogs

Fina

Vignoli²,

Terragni

et al. 2013

Vet Radiology Ultrasound

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Canine pulmonary eosinophilic granulomatosis is a rare inflammatory pulmonary disease characterized by formation of eosinophilic granulomas that tend to obliterate the normal pulmonary architecture. The purpose of this retrospective study was to describe the CT characteristics of confirmed idiopathic pulmonary eosinophilic granulomatosis in a group of dogs. Five dogs met inclusion criteria. All patients were young adult dogs of variable breeds. No dog had concurrent occult heartworm disease. Computed tomographic characteristics most commonly included pulmonary masses and nodules of variable size, and lesions were most commonly located in the caudal lung lobes. Four dogs had large pulmonary masses with or without additional nodules and one dog had nodular lesions disseminated throughout the entire lung parenchyma. All large eosinophilic granulomas were smoothly margined, heterogeneous pulmonary masses displaying heterogeneous contrast enhancement. A honeycomb-like enhancement pattern was observed in all but one mass and consisted of multiple hyperattenuating rims delineating central hypoattenuating areas, suggestive of bronchiectatic lung with peripheral enhancing airway walls and fluid-filled, necrotic bronchial lumen. One dog had evidence of tracheobronchial lymphadenopathy. Findings indicated that canine eosinophilic pulmonary granulomatosis should be included as a differential diagnosis for dogs with CT characteristics of multiple pulmonary masses and/or nodules in caudal lung lobes, and a honeycomb-like enhancement pattern in masses after intravenous administration of iodinated contrast medium.

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Section: Discussioncontrasting

confidence: 60%

Computed Tomographic Characteristics of Eosinophilic Pulmonary Granulomatosis in Five Dogs

Fina

Vignoli²,

Terragni

et al. 2013

Vet Radiology Ultrasound

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“…In human medicine, there are sporadic case reports of mediastinal sarcomas, with one case series of 16 cases of mediastinal sarcomas in which undifferentiated sarcomas were associated with a higher rate of tumour progression and poorer survival times 18 . In the veterinary literature, reported survival times for thoracic STS range from 2 weeks to not reached 11,12 …”

Section: Discussionmentioning

confidence: 99%

“…Visceral STS are infrequently reported in the veterinary literature. There are sporadic case reports of primary STS originating within the thoracic cavity 10–12 . Traditionally, wide surgical excision has been the recommended surgical dose for visceral STS.…”

Section: Discussionmentioning

confidence: 99%

“…18 In the veterinary literature, reported survival times for thoracic STS range from 2 weeks to not reached. 11,12 Some mediastinal masses can be difficult to differentiate from pulmonary masses using imaging, particularly when they are not located along the midline. 19 In this case, the mass was originally classified as most likely pulmonary in origin, given the left-sided caudoventral location and close association with the left caudal lung lobe.…”

Section: Discussionmentioning

confidence: 99%

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Primary mediastinal spindle cell sarcoma in a dog

Lomas

Garrett

Taylor³

et al. 2022

Vet Record Case Reports

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Soft tissue sarcomas are frequently reported tumours in dogs and are most often located in the cutaneous and subcutaneous tissues. Primary thoracic soft tissue sarcomas are infrequently reported in veterinary literature. This case report describes the diagnosis and treatment of a primary mediastinal spindle cell sarcoma of a 7‐year‐old, male, neutered Labrador retriever. Staging was performed before surgery. Computed tomography revealed a large intrathoracic mass in the left ventral hemithorax. A left‐sided thoracotomy was performed and a large pedunculated mass originating from the caudal mediastinum was excised. Histopathology revealed a high‐grade, undifferentiated spindle cell sarcoma. Immunohistochemistry staining confirmed the mesenchymal origin of the mass. Adjuvant chemotherapy was administered. Thoracic radiology was performed 38 days after surgery and revealed pleural effusion and mass effect in the caudal thorax. The patient was euthanased 66 days after surgery due to acute respiratory distress.

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“…tkanek miękkich jamy miednicy lub w płucach (7,20). W badaniach własnych we wszystkich 136 przypadkach obłoniaki były zlokalizowane w skórze lub tkance podskórnej, a precyzyjna lokalizacja była znana u 113 psów (szczegółowe dane dotyczące lokalizacji obłoniaków u psów objętych badaniem przedstawiono w tabeli 3).…”

Section: Ryc 1 Występowanie Obłoniaków W Zależności Od Wieku I Płci Psówunclassified

Haemangiopericytomas in dogs: Epidemiological analysis of 136 cases

Sapierzyński¹,

Czopowicz²,

Stopka³

2019

Medycyna Weterynaryjna

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Perivascular wall tumors (PWTs or haemangiopericytomas) are common in dogs, and they are clinically important in veterinary oncology, but there is no data on the occurrence of these tumors in dogs in Poland. The aim of the present study was an epidemiological analysis of canine perivascular wall tumors. The study included 136 dogs with recognized PWTs (whose frequency of occurrence was the same in females and males). The mean age of the dogs was 9.8±3.0 years, with no statistically significant difference between sexes. Among the dogs, 40.7% were mongrels, and 59.3% were purebred. Among the purebred dogs, 21 (26.3%) were German Shepherds, 17 (21.3%) were Boxers, 5 (6.3%) were Doberman pinchers and Rottweilers. Statistical analysis revealed that four breeds were predisposed to perivascular wall tumors in comparison to the general dog population: German Shepherds, Boxers, Doberman pinchers and Rottweilers. Moreover, large-breed (but not giant-breed) dogs were shown to be predisposed to PWTs. Tumors were located in the skin or subcutis of the entire body, mostly on the legs, more seldom on the trunk or the head. The most typical location for PWTs was the elbow area (11% of all cases).

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Primary pulmonary spindle cell tumour (haemangiopericytoma) in a dog

Cited by 8 publications

References 22 publications

Computed Tomographic Characteristics of Eosinophilic Pulmonary Granulomatosis in Five Dogs

Computed Tomographic Characteristics of Eosinophilic Pulmonary Granulomatosis in Five Dogs

Primary mediastinal spindle cell sarcoma in a dog

Haemangiopericytomas in dogs: Epidemiological analysis of 136 cases

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