Primary Pulmonary Meningioma Simulating a Pulmonary Metastasis

Abstract

Primary pulmonary meningiomas represent a rare tumor entity. Few cases have been reported in the English medical literature, and they have almost all been solitary and benign in nature, with the exception of several extremely rare cases. We report herein a case of PPM that raised suspicion of a pulmonary metastatic tumor initially, as it was depicted as a single, round, small, ground-glass opacity pulmonary nodule on a chest computed tomography scan, in a 55-year-old man with a history of buccal cancer. Increased awareness of the clinical and radiologic characteristics of this rare category can assist a multidisciplinary team to perform adequate management.

A case of a primary pulmonary meningioma mimicking a metastasis from a papillary thyroid carcinoma due to a size reduction after radioactive iodine therapy

“…PPMs are rare and only 46 cases (including our case) have been reported in English literature since the first case was described in 1981 [7]. Most of those cases were asymptomatic, grew slowly, and had an excellent prognosis with an unknown etiology.…”

“…Primary pulmonary meningiomas (PPMs) are a rare and mostly benign disease and often present as a solitary pulmonary nodule [1,2]. Because most PPMs grow in size without any specific radiological features, it is quite difficult to distinguish them from metastatic lung tumors in patients with a history of a malignancy [3][4][5][6][7]. We described a case of a PPM initially suspected as a metastasis from thyroid cancer due to a size reduction after radioactive iodine therapy.…”

A case report of primary pulmonary meningioma masquerading as lung metastasis in a patient with rectal carcinoma: role of 18F-FDG PET/CT

“…In this study, we report an extremely rare disease, PPM, which shows no significant uptake of 18 F-FDG on PET/CT scan, a feature that has never been reported before. It is often misdiagnosed as lung metastasis owing to the difficulty of distinguishing the two pathologies on conventional chest CT scan and sometimes due to the high uptake of 18 F-FDG on PET/CT scan [ 4 , 8 , 10 ]. In our case, it was first regarded as lung metastasis of rectal carcinoma owing to the presentation of solitary pulmonary nodular with well-defined boundary on CT images.…”

Primary pulmonary meningioma mimicking pulmonary metastasis: A rare case report

“…[ 5 ] In addition, PPM and meningothelial-like nodules show similar histomorphological and immunohistochemical properties; however, genotype characteristics may be different. [ 2 , 4 ] Furthermore, controversial results were reported regarding the incidences of meningioma and meningothelial-like nodules in autopsy series (0.5% vs. 0.05%, respectively).…”

“…[ 1 ] APPM is usually benign and often appears as a solid pulmonary nodule on chest radiography and computed tomography (CT), which is incidentally detected in the majority of cases. [ 2 ]…”