Primary Pulmonary Hodgkin’s Lymphoma

Abstract

A 21-year-old man presented to hospital with a two-month history of productive cough with no other symptoms. Radiology revealed a cavitating lesion in the left upper lobe for which a variety of diagnoses were considered. A biopsy revealed primary pulmonary Hodgkin's lymphoma. Primary pulmonary Hodgkin's lymphoma is an uncommon initial presentation; lung lesions usually occur later in the course of the disease. Following diagnosis, the patient began chemotherapy and full remission was achieved.

Giant thoracic mass: an unusual presentation of primary pulmonary Hodgkin's lymphoma

“…The diagnosis of PPHL requires three criteria to be fulfilled: (1) the disease should be restricted to the lung in which the neoplastic process arises; (2) histological results consistent with Hodgkin's lymphoma should be present; and (3) other possible pathological causes should be excluded 1 4…”

“…Pulmonary involvement is reported to occur in 15–40% of patients with Hodgkin's disease 1. However, the presentation of primary pulmonary Hodgkin's lymphoma (PPHL) is very rare, with just over 70 cases recorded internationally between 1927 and 2006 1…”

Pulmonalis eltérések Hodgkin-lymphomában

“…A nodulusok járhatnak üregképződéssel, lehetnek szoliterek, illetve multinodularisak. Ritkábban a nyirokutak mentén, mint interstitialis infiltráció észlelhe-tünk pulmonalis HL-t [9][10][11].…”

“…A változatos megjelenés és a nem specifikus kép differenciáldiagnosztikai nehézséget jelenthet [10,13,15] (1. táblázat). A következőkben a különböző morfológiai megjelenési formákra hozunk egy-egy esetet saját betegeink közül.…”

Pathologie primär pulmonaler Lymphome

“…Abb. 3), kann in seltenen Fäl-len aber auch primär in der Lunge auftreten [15,16,17]. Betroffen sind wiederum oft immundefekte Patienten, und das cHL in der Lunge ist gelegentlich Folge einer lymphoproliferativen Erkrankung nach Transplantation.…”