Primary pulmonary collision tumor including squamous cell carcinoma and T-cell lymphoma

Kawashima, Osamu; Sakata, Satoko; Kamiyoshihara, Mitsuhiro; Maeshima, Akiko Miyagi; Ishikawa, Susumu; Morishita, Yasuo

doi:10.1016/s0169-5002(98)00100-7

Cited by 27 publications

(31 citation statements)

References 11 publications

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“…Since 1991, only 14 cases of T-cell PPL have been reported, the majority in non-Anglo-Saxon countries. We have reviewed the cases of 12 of these patients, in whom the diagnosis was confirmed histologically [3][4][5][6][7][8][9][10][11][12][13][14]. Their characteristics are summarized in Table 1.…”

Section: Discussionmentioning

confidence: 99%

“…The most frequent radiological findings were bilateral pulmonary nodules [3,6,8,11,13,14], which tend to occur in pulmonary lymphomas of AIDS patients [1]. Other alterations included mass-like consolidations [4,9,12], lesions like those in organized cryptogenetic pneumonia [5,10] and pleural effusion [4]. The transbronchial biopsy, unlike in our case and that reported by Maehara et al [4], did not permit the diagnosis to be established in 10 of the 12 cases reviewed.…”

Section: Discussionmentioning

confidence: 99%

“…The transbronchial biopsy, unlike in our case and that reported by Maehara et al [4], did not permit the diagnosis to be established in 10 of the 12 cases reviewed. In the majority, the diagnosis was confirmed by open lung biopsy [5,6,8,10,11,13] or by lung resection [7,9,12]. The other two patients were diagnosed by means of a cervical lymphoadenopathy biopsy [3] and post-mortem examination [14].…”

Section: Discussionmentioning

confidence: 99%

“…Systemic corticoids were employed temporarily in one patient before conducting an open lung biopsy [5], and in another case a radiological and clinical response was obtained without chemotherapy [10]. Surgical resection was performed in three cases [7,9,12]. In two of these, the tumour was localized and lobectomy proved curative.…”

Section: Discussionmentioning

confidence: 99%

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Bilateral pulmonary nodules as a manifestation of primary pulmonary T-cell lymphoma

2009

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Primary pulmonary lymphoma (PPL) is an uncommon pathology and is usually of the B-cell type, originating in lymphoid tissue associated with the bronchial mucosa (MALT/BALT lymphoma). Very few cases of T-cell PPL, the majority diagnosed by open lung biopsy, have been described in medical literature. We report a case of an immunocompetent patient with fever and bilateral pulmonary nodules, diagnosed with T-cell PPL by transbronchial biopsy. The patient's condition deteriorated and she responded poorly to chemotherapy. PPL should be included in the differential diagnosis of patients with fever and bilateral pulmonary nodules.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Bilateral pulmonary nodules as a manifestation of primary pulmonary T-cell lymphoma

2009

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“…Collision tumors have been described between chronic lymphocytic leukemia (CLL) and invasive ductal carcinoma of the breast [1], T-cell lymphoma and squamous cell carcinoma of the lung [2], Hodgkin's disease and metastatic breast or cervical cancer [3,4], Non-Hodgkin lymphoma and Kaposi sarcoma [5], mucosa-associated lymphoid tissue (MALT) lymphoma with gastric adenocarcinoma [6][7][8] or breast invasive ductal carcinoma [9], among other combinations. Collision lymphomas, especially those between T and B-cell lymphomas occur rarely.…”

Section: Introductionmentioning

confidence: 99%

Collision Anaplastic Large Cell Lymphoma (T-Cell/Histiocyte-Rich) and Diffuse Large B Cell Lymphoma: A Pathologic and Clinical Evaluation

Rajappannair¹,

Lam²,

Benson³

et al. 2012

JCT

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A collision tumor of T and B-cell lymphomas occur rarely. In this article we report a collision tumor of anaplastic large cell lymphoma and diffuse large B cell lymphoma in a 46 years old female. The tumor showed predominantly neoplasmtic anaplastic large cell lymphoma (ALCL) component expressing CD30 and ALK with smaller areas of CD20+ diffuse large B cell lymphoma component. Polymerase chain reaction for T-cell receptor beta and IgH (VDJ) gene rearrangements detected a clonal T cell and a clonal B cell population. The patient developed CSF involvement approximately 3 months after treatment. CSF analysis at this time showed only monoclonal T cells, probably due to clearing of the B cell component by the chemotherapy. To the best of our knowledge this is the first case report of a composite tumor of ALCL (lymphohistiocytic variant) and DLBCL. This case raises issues related to the classification of these composite lymphomas and the treatment on initial presentation and during relapse.

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Case of a lung collision tumor consisting of squamous cell carcinoma of the lung and diffuse large B‐cell lymphoma

Sato

Sakon

Tanaka

et al. 2022

Clinical Case Reports

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Primary pulmonary collision tumor including squamous cell carcinoma and T-cell lymphoma

Cited by 27 publications

References 11 publications

Bilateral pulmonary nodules as a manifestation of primary pulmonary T-cell lymphoma

Bilateral pulmonary nodules as a manifestation of primary pulmonary T-cell lymphoma

Collision Anaplastic Large Cell Lymphoma (T-Cell/Histiocyte-Rich) and Diffuse Large B Cell Lymphoma: A Pathologic and Clinical Evaluation

Case of a lung collision tumor consisting of squamous cell carcinoma of the lung and diffuse large B‐cell lymphoma

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