Primary prevention of natural rubber latex allergy in health care workers

Allmers, H.; Schmengler, J.; Skudlik, Christoph

doi:10.1016/s0091-6749(03)80256-7

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“…Sri-Akajunt et al [130] carried out personal incidence of latex sensitisation in Germany decreased nationalgloves reduces natural rubber latex-allergic symptoms and markly. [141] ers of sensitisation in employees. It is possible for adequate secondary prevention including job modifications to enable A recent Court of Appeal judgement in England, (Dugmore vs healthcare workers with natural rubber latex allergy to remain at Swansea NHS Trust and another, 2002) has clarified the duty of an their jobs, [137,147] and this is associated with fewer adverse socioemployer to prevent exposure to powdered latex glove use and to economic consequences.…”

Section: Cross-reactivity With Food Allergens (Latex Fruit Syndrome)mentioning

confidence: 99%

Toxicological and Immunological Aspects of Occupational Latex Allergy

Adisesh

2004

Toxicological Reviews

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Latex allergy continues to be an important occupational health problem as latex products are used increasingly worldwide, particularly in healthcare. Although there are few epidemiological studies on the incidence of latex allergy, there has been an increase in the number of case reports over the last 10 years and, based on skin-prick tests, estimates of prevalence of latex allergy in healthcare workers range from 2% to 17%. The allergic health effects arise either from the latex proteins, generally causing a type I immediate hypersensitivity reaction, or from the chemicals added to latex during processing, causing a type IV delayed hypersensitivity reaction. Clinical manifestations of latex allergy depend on the route of exposure and occur by direct contact either with skin or mucosa, or by inhalation. The diagnosis of latex allergy is based on the history, skin tests, serological tests and challenge tests. Thirteen latex allergens have been identified and isolated so far from natural rubber latex. They differ in their potential to elicit immunological responses in individuals allergic to latex and thus have been designated as major or minor allergens. In latex gloves, cornstarch powder used as a donning agent carries latex proteins, thereby increasing inhalational and mucosal exposure to latex proteins. There also appears to be a positive correlation between protein content and allergenicity of gloves. The use of powder-free, low-protein gloves is effective in reducing symptoms and markers of sensitisation. Alternatives to latex gloves, such as nitrile or vinyl gloves are available but may be inferior in respect to manual dexterity and biological impermeability.

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Section: Cross-reactivity With Food Allergens (Latex Fruit Syndrome)mentioning

confidence: 99%

Toxicological and Immunological Aspects of Occupational Latex Allergy

Adisesh

2004

Toxicological Reviews

View full text Add to dashboard Cite

show abstract

Primary prevention of natural rubber latex allergy in health care workers

Cited by 1 publication

References 0 publications

Toxicological and Immunological Aspects of Occupational Latex Allergy

Toxicological and Immunological Aspects of Occupational Latex Allergy

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