Primary Pleomorphic Adenoma of the External Auditory Canal Diagnosed by Fine Needle Aspiration Cytology

Gerber, Claude; Zimmer, George; Linder, Thomas; Schuknecht, Bernhard; Betts, David R.; Walter, Roland B.

doi:10.1159/000331106

Cited by 19 publications

(15 citation statements)

References 7 publications

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“…In general, CT revealed the tumours as well defined with no erosion of adjacent bone. MRI also revealed a well-defined margin, as well as hypointensity on T1-weighted images and hyper-to low intensity on T2-weighted images (Table 1) [4,5,7,8]. The tumours were enhanced by contrast material.…”

Section: Discussionmentioning

confidence: 93%

“…There was no sex predilection. Common symptoms related to primary PA of the EAC included obstruction of the EAC meatus, hearing loss, otalgia, and otorrhoea [3][4][5][6][7][8][9][10][11][12][13].…”

Section: Discussionmentioning

confidence: 99%

“…Thus, pathological diagnosis is required to differentiate between benign and malignant tumours such as adenocarcinoma and adenoid cystic carcinoma. Although there is a report that fine-needle aspiration cytology contributes to preoperative diagnosis of PA [4], preoperative incisional biopsies were performed in most previously reported cases. In our case, preoperative fine-needle aspiration cytology findings were typical of PA.…”

Section: Discussionmentioning

confidence: 99%

“…However, PA may also arise from the external auditory canal (EAC), although reports are very rare. Since 1951, when Mark and Rothberg published their first EAC pleomorphic adenoma report [2], at least 35 similar cases have been reported [3][4][5][6][7][8][9][10][11][12][13]. PA of the EAC is classified as a type of ceruminal gland tumour.…”

Section: Introductionmentioning

confidence: 99%

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Ceruminous Pleomorphic Adenoma of the External Auditory Canal: Two Case Reports and Review of the Literature

Chung¹,

Lee²,

Choi³

2017

Korean J Otorhinolaryngol-Head Neck Surg

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Background. Pleomorphic adenoma (PA) is a benign tumour that mainly arises from salivary glands, and PA of the external auditory canal (EAC) is very rare. The objective of this study was to clarify the clinical presentation and treatment of PA of the EAC. Method. The authors present a case of PA arising from the EAC together with a literature review. Results. A 40-year-old man complained of hearing loss and foreign-body sensation of the right ear. Clinical and radiological examinations revealed a welldefined tumour limited to the EAC, with no connection to the parotid gland. Preoperative fine-needle aspiration cytology findings were characteristic of PA. The tumour was removed en bloc with the overlying skin. Conclusion. PA of the EAC is very rare, and methods to rule out malignancy before treatment are lacking. Thus, long-term follow-up is necessary, because malignant tumours are common in the EAC and PA has malignant potential.

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Ceruminous Pleomorphic Adenoma of the External Auditory Canal: Two Case Reports and Review of the Literature

Chung¹,

Lee²,

Choi³

2017

Korean J Otorhinolaryngol-Head Neck Surg

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“…Since the first description of mixed tumor affecting the EAC, in 1951 by Mark and Rothberg, 8 there have been < 30 documented cases in the literature, 5,9 with the patients' ages ranging from 15 to 80 years (mean, 50.5) and no sexual predilection. This makes the patient in our report the youngest.…”

Section: Discussionmentioning

confidence: 99%

Role of FNAC in Metastasizing Malignant Mixed Tumor of the External Auditory Canal

Goh

Chuah²,

Tan³

et al. 2003

Acta Cytologica

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Diagnostic reliability of FNAC for salivary gland swellings: A comparative study

Ashraf

Shaikh

Kamal

et al. 2009

Diagnostic Cytopathology

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A prospective study was conducted to see the sensitivity, specificity, and accuracy of fine needle aspiration cytology (FNAC) for 100 salivary gland swellings in comparison with biopsy. These randomized samples were submitted and reported at the department of pathology, Allama Iqbal Medical College, Lahore. The male to female ratio was 1:1.5. Ages of the patients ranged from 8.5 to 58 years with mean age 33.39 +/- 12.37 years. Maximum number of lesions was found in age group between 21 and 40 years. Parotid gland was involved in 68%, submandibular gland in 30%, and minor salivary glands in 2% patients. Sublingual gland was not involved in any of our subjects. There were 14% cases of non-neoplastic lesions and 86% cases of neoplastic lesions on biopsy. Non-neoplastic lesions included 12 cases of inflammations (three cases of granulomatous inflammation and nine cases of nonspecific chronic inflammation) and two cases of inclusion cysts. Among neoplastic lesions, biopsy revealed 68 cases of benign neoplasia and 18 cases of malignant neoplasia. Non-neoplastic lesions did not show any difference in diagnosis by both techniques. FNAC misdiagnosed four malignant and one benign lesion. Sensitivity, specificity, positive predictive value, and negative predictive value of FNAC for benign neoplastic lesions were 98.52, 87.05, 94.36, and 96.55%, respectively, whereas for malignant neoplastic lesions they were 77.77, 98.78, 93.33, and 95.29%, respectively. In conclusion, FNAC is found to be a highly sensitive and specific technique for diagnosis of most of salivary gland swellings, except for malignant neoplastic lesions where its sensitivity is intermediate. We strongly recommend that FNAC should be adopted as an initial investigation for all salivary gland swellings.

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Primary Pleomorphic Adenoma of the External Auditory Canal Diagnosed by Fine Needle Aspiration Cytology

Cited by 19 publications

References 7 publications

Ceruminous Pleomorphic Adenoma of the External Auditory Canal: Two Case Reports and Review of the Literature

Ceruminous Pleomorphic Adenoma of the External Auditory Canal: Two Case Reports and Review of the Literature

Role of FNAC in Metastasizing Malignant Mixed Tumor of the External Auditory Canal

Diagnostic reliability of FNAC for salivary gland swellings: A comparative study

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