Primary Phycomycosis of the Brain in Heroin Addicts

Kasantikul, Vira; Shuangshoti, Samruay; Taecholarn, Chopeow

doi:10.1007/978-3-662-11152-9_106

Cited by 2 publications

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“…In 1970, Hameroff et Al described the association between mucormycosis and IV drug use 11 . Due to the rising number of IV drug abusers, there has been an increased prevalence of this presentation of disease 2,5,[12][13][14][15][16][17][18][19] . Isolated cerebral mucormycosis is an uncommon presentation of this fungal infection, having a high mortality rate 18 and a predilection for diabetics, immunocompromised patients and IV drug abusers.…”

Section: Discussionmentioning

confidence: 99%

Imaging of Isolated Cerebral Mucormycosis

et al. 2007

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Mucormycosis is a rare infection in immunosupressed patients caused by fungi from the family Mucoraceae. Three types of disease spread have been described: rhinocerebral, systemic and isolated. Isolated spread is the most uncommon form, usually resulting in death. It has been described in diabetics, immunosupressed patients and intravenous drug abusers. Neuroimaging can aid the diagnosis of this entity, but biopsy remains the only reliable method. Imaging findings of Mucormycosis include abscesses and hemorrhagic or ischemic infarcts, usually in the basal ganglia and frontal lobes. Single or multiple lesions have been described as well as meningoencephalitis. Understanding these findings can help to detect the infection in an early stage. We describe three cases of isolated cerebral mucormycosis; all of them were intravenous drug abusers with one patient also being HIV positive.

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Section: Discussionmentioning

confidence: 99%

Imaging of Isolated Cerebral Mucormycosis

et al. 2007

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“…In patients with malignancy-associated isolated cerebral mucormycosis (without rhino-orbital focus), the infection often disseminates hematogenously from the pulmonary system [2 -6]. Patients with isolated cerebral mucormycosis without predisposing disease mostly have history of intravenous drug abuse (IVDA) ( [7][8][9][10][11][12][13][14][15][16][17][18][19][20], Table 1); the fungus is likely transmitted hematogenously from the venous port.…”

Section: Introductionmentioning

confidence: 99%