Primary perirenal angiosarcoma: A rare presentation of a perirenal mass

Samadi, Katayoun; Arellano, Ronald S.

doi:10.1016/j.radcr.2018.09.013

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…Angiosarcoma is a malignant vascular neoplasm which may occur in any location of the body, including the skin, soft tissue, breast, bone and visceral organs including the liver. Primary renal angiosarcoma is very rare, with about 70 cases described in the literature to date [49][50][51][52][53][54][55][56][57]. Most of these cases are seen in older men, with a peak incidence in the sixth to seventh decades and a pronounced male predilection (male-to-female ratio of 7:1) [49].…”

Section: Angiosarcomamentioning

confidence: 99%

“…The management of renal angiosarcoma is controversial and not wellestablished; most patients were treated with radical nephrectomy followed by varying combinations of radiation and chemotherapy [51]. One recent study describes a case treated with neoadjuvant chemoradiation with excellent response, demonstrating potential for this therapeutic approach in future cases [56]. While targeted treatment with anti-angiogenic factors has been utilized with some success in non-renal angiosarcomas, two cases of renal angiosarcoma treated with recombinant interleukin-2 and bevacizumab ultimately resulted in death from disease [49,58].…”

Section: Angiosarcomamentioning

confidence: 99%

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Vascular Neoplasms and Related Lesions of Kidney

Lin¹,

Ro²

2020

ann urol oncol

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Vascular tumors arising in the kidney are distinctly uncommon occurrences and have not been well-characterized in the literature; most cases have been documented in single reports or small case series. These tumors often exhibit nonspecific clinical and radiologic features and may mimic malignant epithelial tumors such as renal cell carcinoma (RCC) on imaging studies, necessitating nephrectomy with pathologic examination for definitive diagnosis. In addition, since primary renal vascular tumors are rare and infrequently encountered in surgical pathology specimens, they are often not considered in the differential diagnosis and therefore may be systematically under-diagnosed. In this review, we discuss the clinical and morphologic features of benign, borderline, and malignant vascular neoplasms and related lesions arising in the kidney, with a focus on recent, clinically relevant advances in imaging, histopathologic diagnosis, and treatment.

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