Primary Parapharyngeal Space Tumors in a Mexican Cancer Center

Ortíz, Kuauhyama Luna; Navarrete-Alemán, Jaime Esteban; Granados-García, Martín; Herrera‐Gómez, Ángel

doi:10.1016/j.otohns.2005.01.013

Cited by 63 publications

(57 citation statements)

References 14 publications

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“…The authors present a case of extensive polymorphic adenoma of the parapharyngeal space with penetration to the skull base, confirming the reports of other researchers about the asymptomatic development of tumours in that region in the early stages of the disease [2][3][4].…”

Section: Discussionsupporting

confidence: 85%

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Extensive pleomorphic adenoma of parapharyngeal space with pterygopalatine fossa and skull base penetration –

Gierek¹,

Paluch²,

Markowski³

et al. 2010

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The authors present a very rare case of a giant pleomorphic adenoma arising from the parapharyngeal space with penetration to the pterygopalatine fossa and skull base in a 62-year old patient. The authors put emphasis on diagnostic and surgical treatment of tumours in this anatomical region. It is necessary for surgical treatment of tumours in this area to be carried out by a multi-specialty laryngological-neurosurgical team, having long-term experience in skull base surgery.

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Section: Discussionsupporting

confidence: 85%

“…Ranking second in frequency of occurrence is the group of neurogenic non-malignant tumours: ganglioneuroma, neurofibroma, paraganglioma, neurilemoma; as well as malignant ones: neurofibrosarcoma, schwannosarcoma, sympathicoblastoma [4].…”

Section: Introductionmentioning

confidence: 99%

Extensive pleomorphic adenoma of parapharyngeal space with pterygopalatine fossa and skull base penetration –

Gierek¹,

Paluch²,

Markowski³

et al. 2010

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show abstract

“…The transoral approach presents a direct route to tumors though the oropharynx, but provides no control of the large blood vessels (6). This approach may be useful for small benign avascular tumors that present in the oropharynx and do not extend to the styloid process (14,19,25,26). However, other authors have reported that this approach for PPS tumor was associated with a 25% recurrence rate within 5 years (27).…”

Section: Discussionmentioning

confidence: 99%

Surgical treatment of parapharyngeal space tumors: A report of 29 cases

Ijichi

Murakami

2017

Oncology Letters

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Abstract. The present study aimed to establish a strategy for parapharyngeal space (PPS) tumor surgery based on preoperative symptoms, clinical signs, imaging and histological examination. A retrospective cohort study was conducted with 29 adult patients who underwent surgery for primary PPS tumors from 2008-2015. The following data was obtained: Preoperative symptoms of the patient, histological type of the tumor, surgical approach and complications. Of the 29 patients who underwent surgery to remove a PPS tumor, 16 presented with neurogenic tumors and 13 with salivary gland tumors. The most common symptom was the presence of a neck mass. Preoperative computed tomography and magnetic resonance imaging were performed to evaluate the size and location of the tumors. The majority of the salivary gland tumors were located in the prestyloid space, whereas all neurogenic tumor cases were poststyloid. A total of 21 of the 29 patients (72.4%) underwent a preoperative fine needle aspiration (FNAC) examination. FNAC contributed to preoperative diagnosis in 9 of these cases (42.9%). In parotid tumors of the prestyloid space, facial nerve palsy was a common postoperative complication. In the case of neurogenic tumors, a common complication was the postoperative palsy of the nerve of tumor origin. The strategy for PPS surgery, from the preoperative diagnosis to the operative method, remains controversial. The data on pre-and postoperative symptoms, imaging and histological diagnosis, and the selection of surgical method depending on a neurogenic or salivary tumor origin in the present study indicated that improving the method of examination, carefully selecting the method of approach and accurately managing surgery leads to complete tumor removal, and that the use of nerve-preserving techniques may reduce the likelihood of complications.

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“…However, there remain several researchers who do not hold with this opinion. They consider that FNAB results are not accurate enough (24)(25)(26). Hence, we did not use FNAB in our cases.…”

Section: Discussionmentioning

confidence: 98%

Surgical management and follow-up of lateral skull base tumors: An 8-year review

Kong

Yang

Wang

et al. 2017

Molecular and Clinical Oncology

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Abstract. The purpose of the present article was to describe the diagnostic evaluation of, and surgical approaches to, lateral skull base tumors (LSBTs). The study is a retrospective review of 21 patients diagnosed with tumors that involve lateral skull base (8 with malignant diseases and 13 with benign lesions) who were surgically treated during a 8-year period. The transparotid-transmandibular (38%) was the most commonly performed surgical procedure, followed by the transmandibular (24%), the transmaxillary (24%), the transcervical approach (10%) and the combined approach (4%). The surgical procedures were uneventful and there were no postoperative mortalities. Complications were encountered in 12 cases, and morbidity was not remarkable during the perioperative stages. After an average follow-up of 46 months, only 1 of 14 patients with benign diseases had a recurrence following the resection of a pleomorphic adenoma. Of 7 patients with malignant tumors, 5 are alive with no evidence of disease. The majority of the benign lateral skull base tumors can be removed surgically with a low rate of complications and recurrence. However, malignant neoplasms carry a poor prognosis and a low rate of disease-free survival.

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Primary Parapharyngeal Space Tumors in a Mexican Cancer Center

Cited by 63 publications

References 14 publications

Extensive pleomorphic adenoma of parapharyngeal space with pterygopalatine fossa and skull base penetration –

Extensive pleomorphic adenoma of parapharyngeal space with pterygopalatine fossa and skull base penetration –

Surgical treatment of parapharyngeal space tumors: A report of 29 cases

Surgical management and follow-up of lateral skull base tumors: An 8-year review

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