Primary Pancreatic Lymphoma in a Patient with Maturity Onset Diabetes of the Young type 3

Bozzoli, Valentina; Tisi, Maria Chiara; Pianese, Luigi; Tumini, Stefano; Rufini, Vittoria; Calcagni, Maria Lucia; Pitocco, Dario; Larghi, Alberto; Larocca, Luigi Maria; Massini, Giuseppina; Teofili, Luciana; D’Alo’, Francesco; Hohaus, Stefan

doi:10.4084/mjhid.2012.005

Cited by 2 publications

(2 citation statements)

References 13 publications

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“…Our analysis identified 21 cases of PPL in patients under 18 years of age. 15 , 24 , 30 , 35 , 37 , 51 , 55 , 67 , 70 , 81 , 82 , 84 , 87 , 92 , 96 , 99–102 The mean age was 10.3 (range 3–16) years, with most of patients (19, 90.5%) being males ( Table 5 ).…”

Section: Resultsmentioning

confidence: 99%

Primary Pancreatic Lymphoma: Recommendations for Diagnosis and Management

Facchinelli¹,

Boninsegna

Visco³

et al. 2021

JBM

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Section: Resultsmentioning

confidence: 99%

Primary Pancreatic Lymphoma: Recommendations for Diagnosis and Management

Facchinelli¹,

Boninsegna

Visco³

et al. 2021

JBM

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“…The versatility of 18 F-FDG PET/CT extends to its ability to discern glycometabolic changes within lesions prior to observable anatomical alterations, rendering it an invaluable asset for baseline assessment and the assessment of lymphoma treatment efficacy (5,6,36). In our study, two instances (9,20) unveiled smaller pancreatic lesions that evaded detection via CT and MRI, accompanied by comparatively lower FDG uptake than their larger counterparts. Notably, among our cases, ten subjects underwent post-treatment 18 F-FDG PET/CT evaluations, uncovering two cases of recurrence within the pancreas and peripancreatic lymph nodes.…”

Section: Discussionmentioning

confidence: 67%

18F-FDG PET/CT assists the diagnosis of primary pancreatic lymphoma: Two case reports and literature review

Wang,

Zhou,

Liu

et al. 2024

Front. Med.

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Primary pancreatic lymphoma (PPL) is a rare malignancy, which is defined as a mass centered in pancreas with involvement of contiguous lymph nodes and distant spread may exist. Accurate diagnosis of PPL prior to pathological confirmation remains challenging, underscoring the critical significance of preoperative imaging assessments. This case report collected two instances of PPL that underwent initial evaluation via 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) between August 2021 and July 2022. Correspondingly, pertinent literature encompassing 18F-FDG PET/CT data related to PPL was meticulously reviewed. Including our aforementioned pair of cases, a cumulative total of 25 instances of PPL were assembled. The distinctive profile of 18F-FDG PET/CT images of PPL predominantly manifests as hypermetabolic lesions with diminished density. Primarily characterized by singular lesions and comparatively substantial volumetric dimensions, a total of eleven cases revealed contiguous lymph node engagement, with five instances displaying distant dissemination encompassing lymph nodes in multiple locations. Amongst these, ten patients underwent sequential 18F-FDG PET/CT follow-up post-intervention. In comparison to pancreatic carcinoma, PPL lesions exhibited heightened hypermetabolism, augmented volumetric proportions, and distinct patterns of distant metastasis. This study indicates that the pivotal role of 18F-FDG PET/CT in the diagnosis and assessment of therapeutic efficacy in PPL is unequivocal. Combined with the clinical attributes of patients, the integration of 18F-FDG PET/CT augments the differential diagnostic capacity differentiating PPL from pancreatic carcinoma.

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Primary Pancreatic Lymphoma in a Patient with Maturity Onset Diabetes of the Young type 3

Cited by 2 publications

References 13 publications

Primary Pancreatic Lymphoma: Recommendations for Diagnosis and Management

Primary Pancreatic Lymphoma: Recommendations for Diagnosis and Management

18F-FDG PET/CT assists the diagnosis of primary pancreatic lymphoma: Two case reports and literature review

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