Primary Ovarian Cancer Associated With Pregnancy

Munnell, Equinn W.

doi:10.1097/00003081-196312000-00016

Cited by 67 publications

(21 citation statements)

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“…It is suggested that serial measurements of tumor marker CA125 especially combined with ultrasound, increase the sensitivity of ovarian cancer diagnosis [9]. Some studies suggested removal of ovarian mass during pregnancy for three reasons: 1. elimination of a potential dystocia cause, 2. risk of rupture, torsion and hemorrhage and 3. potential risk of malignancy [10,11]. Considering the risk of miscarriages after surgery and the differential diagnosis of Doppler approach, other studies suggested that exploratory laparotomy only for persistent masses with suspicious for malignancy sonographic characteristics [3].…”

Section: Discussionmentioning

confidence: 99%

Stage IC Ovarian Cancer Diagnosed during Pregnancy: Personalized Management and Literature Review

Sun¹,

Li²,

Zhang³

et al. 2016

Reprod Syst Sex Disord

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Section: Discussionmentioning

confidence: 99%

Stage IC Ovarian Cancer Diagnosed during Pregnancy: Personalized Management and Literature Review

Sun¹,

Li²,

Zhang³

et al. 2016

Reprod Syst Sex Disord

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“…When pelvic sonography was not available three decades ago, tumors were identified as incidental findings during the initial routine prenatal pelvic examinations or at Caesarean section, and consequently the majority of ovarian neoplasms during pregnancy were not detected until they were well advanced (3)(4)(5)(6)(7)15). In our 10 cases, ovarian tumors were all detected by ultrasound and the diagnoses were all made at stage I, demonstrating the distinguished scientific benefit of pelvic sonography.…”

Section: Discussionmentioning

confidence: 99%

“…Although these tumors are relatively asymptomatic, they become evident in a routine ultrasonographic scan (2). Almost three decades ago, pelvic ultrasonography was not available and tumors were discovered as incidental findings during the initial routine prenatal pelvic examinations or at Caesarean section in symptomless patients (3)(4)(5)(6)(7). The prenatal courses were usually uneventful, causing the occasional delayed diagnosis (3) and the difficulty of early detection was emphasized (5).…”

Section: Introductionmentioning

confidence: 99%

Ovarian cancer complicated by pregnancy: Analysis of 10 cases

et al. 2011

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Abstract. The objective of this study was to ascertain the evidence on ovarian cancer during pregnancy and compile recommendations derived from this information. This was a retrospective study, based on clinical histories from patients diagnosed and treated at 4 independent hospitals for ovarian cancer during pregnancy, between 1992 and 2009. The median age at diagnosis was 30 years (range, 24-41). Out of 10 cases of ovarian cancer, 2 patients showed either bleeding or abdominal pain, while 8 patients were asymptomatic. All 10 cases were diagnosed via ultrasound, and the masses were detected in the first trimester in 7 patients and in the second trimester in 2 patients. Of the diagnosed tumors, 8 cases were epithelial tumors including 6 adenocarcinomas and 2 borderline tumors, and 2 germ cell tumors. The primary ovarian malignancies were at stage I of the disease. Unilateral salpingo-oophorectomy was performed in 9 patients and cystectomy was performed in one patient. Chemotherapy was administered to 4 patients, in 1 case during pregnancy. Neonatal outcome analysis showed a full-or pre-term delivery in 6 cases, abortion in 1 case and therapeutic termination in 3 cases. The majority of cases of ovarian cancer in pregnancy were incidentally detected by ultrasound at an early stage, resulting in good prognosis for the mother and the neonate.

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“…Munnell (1963), and Graver and Barber (1973) also indicated that when low grade mucinous cystadenocarcinoma, arrhenoblastoma, dysgerminoma, granulosa theca cell tumor or low grade papillary tumor is observed at its Stage Ia during pregnancy, the disease can be treated only by resection of an affected ovary.…”

Section: Postoperative Coursementioning

confidence: 99%

“…Jubb (1963a) studied 34 patients collected from the reports from eight institutions in Toronto City between 1882 and 1963, and found that a malignancy rate in the ovarian tumors associated with pregnancy was 2.2-5.0%. Munnell (1963) also reported the rate of malignant ovarian tumor in pregnant women is one to 18,000 of delivaries for 15-year period and Chung and Birnbaum (1973), one to 25,000 of delivaries between 1951 and 1970. This paper presents an EST which developed in a patient in the seventh week of pregnancy.…”

mentioning

confidence: 93%