Primary ovarian Burkitt's lymphoma presentation in a young woman: A case report

Sergi, William; Marchese, Tiziana; Botrugno, Ivan; Baglivo, Arturo; Spampinato, Marcello

doi:10.1016/j.ijscr.2021.105904

Cited by 2 publications

(2 citation statements)

References 23 publications

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“…Despite the limited role of surgery in ovarian lymphoma, the majority of reported patients underwent laparotomic or laparoscopic exploration on the basis of the acute clinical presentation and the suspicion of adnexal torsion ( 3 , 21 , 22 ); in the present case, the patient complained of lower abdominal pain that was interpreted as a sign of vascular compression, and surgical exploration was therefore warranted.…”

Section: Discussionmentioning

confidence: 83%

Case report: Primary ovarian Burkitt's lymphoma: A puzzling scenario in pediatric population

et al. 2023

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Burkitt's lymphoma (BL) is defined as a highly invasive B-cell lymphoma, usually characterized by an excellent prognosis, more than 90% of children and adolescents being cured with highly dose-intensive multiagent chemotherapy. Primary ovarian localization without involvement of other organs is a rare manifestation of BL, especially in pediatric population. Symptoms at diagnosis are similar to other ovarian lesions and differential diagnosis may be challenging for clinicians. A 12-year-old girl was referred to our institution for abdominal pain and palpable mass observed by the pediatrician. Diagnostic work-up demonstrated a large mass arising from the right ovary, causing compression on abdominal aorta, inferior vena cava, ureters and bowel, with a second smaller lesion on the left ovary. At surgery, a 15 cm-large, ruptured mass arising from the right ovary was found, associated with a second lesion originating from the left ovary (8 cm) and multiple nodules of the greater omentum. Right salpingo-oophorectomy was performed, incisional biopsies were taken from the left ovary and omental nodules and peritoneal fluid samples were collected for cytology. Pathology revealed a Burkitt lymphoma and the patient underwent chemotherapy according to AIEOP LNH-97 Protocol, group R3 with Rituximab. Preoperative diagnosis of primary ovarian lymphoma is extremely difficult. Surgical exploration is often necessary in patients presenting with acute abdominal or pelvic pain; when the suspicion of primary ovarian lymphoma arises intraoperatively, every effort should be made to minimize invasive procedure in order to enhance post-operative recovery.

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Section: Discussionmentioning

confidence: 83%

Case report: Primary ovarian Burkitt's lymphoma: A puzzling scenario in pediatric population

et al. 2023

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“…Elevated CA-125 is often reported in patients with ovarian lymphoma, frequently above the threshold where SGO/ACOG recommends referral to a gynecologic oncologist for surgical evaluation of adnexal mass. ( Sergi et al, 2021 , Sung et al, 2022 , Kumar et al, 2014 ) CA-125 elevation can also be seen in NHL and may be associated with aggressive disease and lower rates of treatment response ( Memar et al, 2015 ). The use of CA-125 as a prognostic marker or for monitoring treatment response in primary ovarian lymphoma has not been described.…”

Section: Discussionmentioning

confidence: 99%