Primary orbital lymphoma: A case report and review of the literature

Khmamouche, Mohamed Réda; Zerrouk, R.; Hamed, Mazin; Reda, K.; Oubaaz, Abdelbarre

doi:10.1016/j.jfo.2017.03.014

Cited by 2 publications

(9 citation statements)

References 6 publications

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“…These lesions can be an indication of systemic lymphoma or can spontaneously arise primarily in orbit. However, a primary NHL of the orbit is an exceedingly rare presentation, making up approximately 8-10% of extranodal NHL, and in the case of our patient, an even smaller 1% of all NHL in general [ 4 ]. Many cases tend to have unilateral lesions in the extraconal anatomical location.…”

Section: Discussionmentioning

confidence: 97%

“…Many cases tend to have unilateral lesions in the extraconal anatomical location. The typical clinical findings of patients with orbital lymphomas include exophthalmos of the affected eye, swelling, limited eye motility, visual acuity changes, diplopia, eye displacement, and “B-symptoms.” B symptoms are a related group of systemic symptoms, including fever, unexplained weight loss, or night sweats [ 3 , 4 ]. However, in our patient, the first symptom experienced was the sensation of eye dryness and irritation without apparent signs of proptosis until months later.…”

Section: Discussionmentioning

confidence: 99%

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Orbital B-cell Lymphoma Masquerading As Dry Eye Disease

Adithya-Sateesh¹,

Gousy²,

Thimmanayakanahalli³

et al. 2023

Cureus

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Orbital lymphoma is a rare tumor with an incidence of 2.02 per million per year. It can occur as a part of systemic lymphoma or spontaneously arise primarily in orbit. The most commonly reported malignant lymphoma is non-Hodgkin's lymphoma. The typical clinical finding includes exophthalmos, swelling, and limited eye movement. Our patient presented with dryness and irritation of the eye without signs of proptosis until months later. The definitive diagnosis of orbital lymphoma requires a biopsy. Still, imaging studies such as MRI and CT scans play a critical role in distinguishing benign from malignant lesions and invasion of local tissues. The treatment of orbital lymphoma is multidisciplinary, involving surgical resection, radiotherapy, and chemotherapy depending on the histological type of tumor and the presence of metastasis.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Orbital B-cell Lymphoma Masquerading As Dry Eye Disease

Adithya-Sateesh¹,

Gousy²,

Thimmanayakanahalli³

et al. 2023

Cureus

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“…They are considered rare and exhibit a variable clinical presentation. 1,5 Thus, prompt recognition and appropriate multidisciplinary management are crucial factors for patient survival and avoidance of systemic advancement. 5,6 We report two cases of orbital lymphomas in which functional alteration was the first patient symptom when referred to medical care.…”

Section: Discussionmentioning

confidence: 99%

“…1,5 Thus, prompt recognition and appropriate multidisciplinary management are crucial factors for patient survival and avoidance of systemic advancement. 5,6 We report two cases of orbital lymphomas in which functional alteration was the first patient symptom when referred to medical care. In case 1, due to the history of tooth extraction 15 days before, an odontogenic infection clinical impression was raised.…”

Section: Discussionmentioning

confidence: 99%

“…10 In addition, some authors state that an multidisciplinary and integrative approach are a effective way to achieve great outcomes and prevent complications. 5 Since the symptoms of lymphomas in the head and neck area are heterogeneous and exhibit a variable course, maxillofacial surgeons should be aware of the initial clinical presentation and always include lymphoid neoplasms as a differential diagnosis in cases which acute functional alterations are present. An immediate tissue biopsy must be performed to allow an appropriate treatment and avoid future consequences.…”

Section: Discussionmentioning

confidence: 99%

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Initial Manifestation of Orbital Lymphomas: The Role of Early Diagnosis

Torres

Gabrielli

Filho

2021

Journal of Craniofacial Surgery

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Orbital lymphoma is a rare condition with non-specific and variable clinical course. This features are the main obstacle for diagnosis and treatment. A 43-year-old female patient complaining of vision loss and hemiface paresthesia, Proptosis was noted associated with an expansive lesion involving the right temporal lobe and orbital region. Craniotomy was performed to allow orbital decompression and anatomopathogical analysis. Final diagnosis was Burkitt Lymphoma. Patient evolved to death after seven days. A 40-year-old male patient complaining excessive tearing and sight disturbance. Proptosis on the right eye was noticed. Extra-conal expansive lesion was observed. Final diagnosis was mucosa-associated lymphoid tissue lymphoma. Radio and chemotherapy protocol was initiated. In a 3 year follow-up, there are no signs of recurrence or ocular/orbital impairment. Maxillofacial surgeons should be aware of the initial clinical presentation and always include lymphoid neoplasms as a differential diagnosis in cases which acute functional alterations are present.

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Primary orbital lymphoma: A case report and review of the literature

Cited by 2 publications

References 6 publications

Orbital B-cell Lymphoma Masquerading As Dry Eye Disease

Orbital B-cell Lymphoma Masquerading As Dry Eye Disease

Initial Manifestation of Orbital Lymphomas: The Role of Early Diagnosis

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