Primary Non-Hodgkin’s Lymphoma of the Male Urethra

Hofmockel, G.; Dämmrich, J.; García, Hugo; Wirth, Michael; Frohmüller, H.

doi:10.1159/000282781

Cited by 8 publications

(1 citation statement)

References 13 publications

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“…Primary tumors arising from the urethra remain case reportable. Of the cases of primary urethral lymphoma that have been described, 19 cases have been reported in female patients and 7 cases in men, 1 of which was associated with HIV infection [1, 5–7]. Limited clinical experience has resulted in uncertainty concerning the most appropriate form of therapy for this malignancy.…”

Section: Introductionmentioning

confidence: 99%

Diffuse Large B-Cell Lymphoma Transformed from Mucosa-Associated Lymphoid Tissue Lymphoma Arising in a Female Urethra Treated with Rituximab for the First Time

Zahrani¹,

Abdelsalam²,

Fiaar

et al. 2012

Case Rep Oncol

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A 30-year-old female patient presented to the gynecology clinic with a small (painless) swelling at the urethral orifice. She underwent surgical excision of the lesion. Pathological examination revealed non-Hodgkin’s lymphoma of diffuse large B-cell type and mucosa-associated lymphoid tissue type, stage IE. The patient refused radiotherapy. Accordingly, we started CHOP-R chemotherapy. She received a total of 6 cycles of CHOP and 8 cycles of rituximab. Patient follow-up was done 3 months later through CT scan and cytoscopy confirming the complete remission. The patient has been disease-free for 4 years. We reviewed 26 cases of this rare entity reported previously.

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Section: Introductionmentioning

confidence: 99%

Diffuse Large B-Cell Lymphoma Transformed from Mucosa-Associated Lymphoid Tissue Lymphoma Arising in a Female Urethra Treated with Rituximab for the First Time

Zahrani¹,

Abdelsalam²,

Fiaar

et al. 2012

Case Rep Oncol

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Lymphoma at uncommon sites

Young

1999

Hematol. Oncol.

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Radiological assessment of extranodal lymphoma: spectrum of disease

et al. 1997

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Primary extranodal lymphoma manifestation in the narrow sense is the term used to define the primary organ manifestation of a malignant lymphoma, excluding the thymus, spleen, Waldeyer's tonsillar ring, the appendix and Peyer's patches. However, in the clinical routine the term is also used for the secondary organ manifestation of underlying lymphoproliferative disease. Primary extranodal lymphomas are mainly non-Hodgkin lymphomas; there is primary extranodal manifestation of Hodgkin's disease in only about 1% of the cases. Among the extranodal NHL, the highly malignant forms predominate. A major exception is MALT lymphomas, which mainly show low slow growth. In the past, they were considered to be pseudolymphomas because of their slow and localized tumor growth. They were included as an entity of their own for the first time in the Revised European American Lymphoma (REAL) classification of 1994. The incidence data vary between < 10% and 25% for primary extranodal manifestation. The major reason for this is the difference in extranodal regions because of classification. Secondary organ involvement of an NHL occurs in up to 40% of the cases in the long-term course of the disease in primary nodal lymphomas. Secondary organ involvement is frequently diagnosed in AIDS patients who develop an AIDS-related lymphoma (85% of cases). The following contribution reports on the radiological imaging of extranodal lymphoma manifestation in the thoracoabdominal region.

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Primary Non-Hodgkin’s Lymphoma of the Male Urethra

Cited by 8 publications

References 13 publications

Diffuse Large B-Cell Lymphoma Transformed from Mucosa-Associated Lymphoid Tissue Lymphoma Arising in a Female Urethra Treated with Rituximab for the First Time

Diffuse Large B-Cell Lymphoma Transformed from Mucosa-Associated Lymphoid Tissue Lymphoma Arising in a Female Urethra Treated with Rituximab for the First Time

Lymphoma at uncommon sites

Radiological assessment of extranodal lymphoma: spectrum of disease

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