Primary nodular chest amyloidoma: A case report and review of literature

Abstract

Primary nodular chest wall amyloidoma, in which a solitary mass of amyloid is deposited in and around the lungs with no evidence of systemic amyloidosis, is extremely rare, most often asymptomatic, and may resemble primary bronchogenic carcinoma. As a result, there are fewer than 100 cases published in the literature and no controlled clinical trials. Primary nodular chest wall amyloidoma is typically diagnosed either as an incidental radiological finding or after very serious and destructive mass growth at which point late-stage respiratory and pain symptoms finally develop, most often in elderly patients. We present imaging studies of a 61-year-old male patient with an unusually massive and destructive chest wall mass, originating in the chest wall, diagnosed as chest wall amyloidoma by histopathology analysis. Our CT, MRI, and PET scan findings are consistent with and contribute to the developing pattern of imaging characteristics seen in other case studies, which can be used to identify amyloidoma before it becomes destructive using non-invasive imaging analyses.

Isolated pulmonary amyloidoma: A rare cause of solitary pulmonary nodule

“…Management can include surgical resection, which is often required in nodular pulmonary amyloidomas, however, there is risk of recurrence [ 4 ]. Patients with NPA typically have optimistic prognoses [ 19 ].…”

Giant mediastinal bronchial artery aneurysm mimicking mediastinal mass: A case report and brief review of the literature

“…Pathology in the mediastinum typically originate from lymph nodes, thymus, thyroid, esophagus, neurogenic, vascular and germ cell tumor [20] . Rare etiology would include amyloidosis or cardiac mass extending into the mediastinum [21] , [22] , [23] , [24] . Intrapulmonary bronchial artery aneurysm presents with hemoptysis when ruptured into the trachea or airways.…”