Primary Myxoid Leiomyoma of the Liver

Abstract

Herein, we report a case of primary myxoid leiomyoma of the liver. A 60-year-old woman complained of upper abdominal fullness. Computed tomography showed a solid tumor (8 cm) in the liver. The patient underwent right hepatectomy and histological findings from the resected specimen revealed scattered bland spindle cells in a background of exuberant myxoid material. The tumor cells were immunoreactive for smooth muscle actin and desmin. No other lesions were found elsewhere in the body. Thus, the tumor was diagnosed as a primary myxoid leiomyoma of the liver.

Hepatic Myxoid Leiomyoma: A Very Rare Tumor

“…The main differential diagnoses encompass myxoma and mesenchymal hamartoma, the latter composed of loose connective tissue and epithelial bile duct or ductile-like in different proportions, with myxoid or collagenous stroma and arranged in a concentric way around the ducts [2]. Extensive tumor sampling is required in order to document the morphological spectra needed for the final diagnosis.…”

“…Primary liver cancer is the sixth most prevalent cancer worldwide, accounting for 5.7% of the overall incidence of cancer [1]. In 2018, the American Cancer Society estimated that liver and intrahepatic bile duct neoplasia corresponded to 4% of all new cases of cancer in men, with an estimated death rate of 6% among men and 3% among women [2, 3].…”

A Firm Hepatic Mass Cannot Be Penetrated by US-Guided Needle Biopsy

“…오 늘날까지 전 세계적으로 문헌으로 보고된 원발성 간 평활근종 의 증례는 36예에 불과하다 [3]. 저자가 아는 한 국내 문헌으로는 오직 두 개의 증례만이 보고되었다 [4]. 발생 빈도가 드물기 때문 에, 원발성 간 평활근종의 진단과 치료, 생물학적 성향에 대해 는 아직 확립되어 있지 않고, 그 이해를 위해서는 더 많은 연구 가 필요하다 [5,6]…”

Fibroblastoid and Myofibroblastoid Tumors of the Liver and Bile Ducts

“…The differential diagnosis comprises few other hepatic mesenchymal tumors that have a myxoid tissue component, including primary hepatic myxoid leiomyosarcoma (Tsiatis et al 2008), primary myxoid leiomyoma (Choi et al 2014), and primary myxoid liposarcoma (Binesh et al 2012). Right atrial metastasis of hepatocellular carcinoma can mimic atrial myxoma (Chua et al 1986;Anwar et al 2010).…”