Primary Mesenteric Smooth Muscle Tumor: An Entity with Unpredictable Biologic Behavior

Kalogiannidis, Ioannis; Stavrakis, Thomas; Amplianitis, Ioannis; Grammenou, Sophia; Mavromatidis, Georgios; Rousso, David

doi:10.1155/2013/483689

Cited by 5 publications

(11 citation statements)

References 10 publications

(17 reference statements)

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“…Solid primary tumors of the mesentery are rare neoplasms among intraabdominal soft tissue tumors and commonly these tumors are smooth muscle tumors and GISTs [1]. Many tumors are also seen in this location including fibromatosis, liposarcoma, malignant fibrous histiocytoma, and peripheral nerve sheath tumors [1,[3][4][5]. Primary solid mesenteric tumors consist of histological heterogenous group of neoplasms [1].…”

Section: Discussionmentioning

confidence: 99%

“…Many tumors are also seen in this location including fibromatosis, liposarcoma, malignant fibrous histiocytoma, and peripheral nerve sheath tumors [1,[3][4][5]. Primary solid mesenteric tumors consist of histological heterogenous group of neoplasms [1]. They usually arise de novo and are seen in adults [6].…”

Section: Discussionmentioning

confidence: 99%

“…The behaviour of mesenteric smooth muscle tumours seems to be unpredictable. Because when they arise large diameters, they usually behave like a malignant tumor even in the absence of nuclear atypia, tumor cell necrosis, or increased mitotic count [1,10]. In the differential diagnosis, parasitic leiomyoma and benign metastasizing leiomyoma must be keep in mind [11,12].…”

Section: Discussionmentioning

confidence: 99%

“…Solid primary tumors of mesenteric origin are quite rare among the intraabdominal soft tissue tumors [1]. The most frequent tumors are Gastrointestinal Stromal Tumors (GIST) and smooth muscle tumors.…”

Section: Introductionmentioning

confidence: 99%

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Mesenteric Fibromyoma Mimicking a Colon Tumor: A Diagnostic Dilemma

Öztürk¹

2014

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Introduction: Solid primary tumors of mesenteric origin are quite rare among the intraabdominal soft tissue tumors. The most frequent tumors are Gastrointestinal Stromal Tumors (GIST) and smooth muscle tumors. GISTs as the largest group of these tumors are usually seen in the wall of gastrointestinal tract and 25% of them are malignant. They usually occur in adults and there is no sexual predominance. We present a huge intra-abdominal myoma clinically mimicking GIST. Case Report: A 49-years old male was referred to our deparment because of a growing mass and pain in the right lower quadrant. Physical examination revealed a huge mass with 10 cm in diameter in the right lower quadrant. Computed tomography (CT) revealed a mass with 17 cm in diameter which originated from caecum and extented from umblicus to urinary bladder and right colon. The mass was resected en-bloc with right hemicolectomy. The final diagnosis is ''Fibromyoma of the mesentery''. Discussion: They usually arise de novo and are seen in adults. Myofibroma can occur as a solitary form or it can be seen as multiple lesions like generalized form which is described as myofibromatozis. Myofibromas are characteristically circumscribed masses with a nodular or multinodular growth pattern and they usually show a biphasic growth pattern. The behaviour of mesenteric smooth muscle tumours is unpredictable. Because they arise large diameters and they can cause different clinical symptoms like obstruction and abdominal pain. The treatment of mesenteric fibromyoma is complete resection. Large intraabdominal solid masses pose a diagnostic challenge either grossly or microscopically. Histopathologically, huge benign fibromyomas should be kept in mind of differantial diagnosis of GİSTs.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Mesenteric Fibromyoma Mimicking a Colon Tumor: A Diagnostic Dilemma

Öztürk¹

2014

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“…Primary tumors arising in the mesentery have been reported as rare tumors; however, small primary tumors are being identified more easily as diagnostic imaging systems have improved. These tumors are typically mesenchymal: Paraganglioma ( 1 , 2 ), lipoma ( 3 ), Schwannoma ( 4 , 5 ), leiomyosarcoma ( 6 ), liposarcoma ( 7 ), osteosarcoma ( 8 ), gastrointestinal stromal tumors (GIST) ( 9 ), solitary fibrous tumors (SFT) ( 10 ), hemangioma ( 11 ), lymphangioma ( 12 ), smooth muscle tumors ( 10 ) and several types of cystic tumors ( 13 ). The majority of patients with primary tumors arising in the mesentery present with abdominal pain, and ultrasonography and/or abdominal computed tomography (CT) and/or magnetic resonance imaging (MRI) are performed.…”

Section: Introductionmentioning

confidence: 99%

A mesenteric solid tumor with unusual features in a young male: A case report

Ichikawa

Maeda

Mizojiri

et al. 2017

Molecular and Clinical Oncology

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The current study presents a mesenteric mesenchymal tumor case, with unusual features in diagnostic imaging and histology. A 16-year-old male was admitted to the hospital with abdominal pain. Computed tomography (CT) revealed an abdominal mass, 2 cm in diameter. The results of contrast-enhanced CT, magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography indicated no specific features suggestive of its histology. Two arteries branching from the superior mesenteric artery were observed feeding the hypervascular tumor. After endoscopic and other laboratory findings revealed no additional lesions, the lesion was diagnosed as a primary mesenteric tumor. As the possibility of malignancy and future bleeding from this tumor could not be ruled out, a resection of the tumor was performed. During the surgery, the tumor, which was well circumscribed and hypervascular, was located in the mesentery of the jejunum. The resected tumor did not exhibit typical histological characteristics, and was labeled as ‘myxoid smooth muscle neoplasm of uncertain biologic potential’. At 2 years after surgery, the patient remained well without evidence of recurrence. As primary mesenteric tumors are rare, particularly in young patients, it is considered important that this type of unusual tumor be included in the differential diagnosis for mesenteric tumors.

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Leiomyomatosis peritonealis disseminata in postmenopausal women: a case report with review of literature

Gebresellassie¹

2016

IMCRJ

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BackgroundLeiomyomatosis peritonealis disseminata is an exceedingly rare benign disorder characterized by multiple vascular leiomyomas growing along the submesothelial tissues of the abdominopelvic peritoneum. It is commonly described in women of reproductive age and is rarely seen in men and postmenopausal women.Case detailsA 65-year-old female patient with a history of abdominal surgery for gastrointestinal stromal tumor presented with abdominal pain, weakness, weight loss, and vomiting. An examination revealed a chronically sick looking, emaciated patient with a long midline abdominal scar, and tenderness on deep palpation all over the abdomen. Ultrasound revealed diffuse intra-abdominal masses and a big liver mass. On laparotomy, innumerable masses were found to arise from the outer walls of whole small intestine and mesentery, and there was a soft, 8×10 cm size liver mass. Histology showed highly cellular interlacing bundles of proliferating smooth muscle cells not associated with nuclear atypia or mitotic figures, and there was no necrosis seen, suggesting cellular leiomyoma.ConclusionLeiomyomatosis peritonealis disseminata is a very rare condition, especially in men and postmenopausal women. It should be considered as a differential in patients with disseminated intra-abdominal masses arising in mesentery, peritoneum, and on walls of the intestine.

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Primary Mesenteric Smooth Muscle Tumor: An Entity with Unpredictable Biologic Behavior

Cited by 5 publications

References 10 publications

Mesenteric Fibromyoma Mimicking a Colon Tumor: A Diagnostic Dilemma

Mesenteric Fibromyoma Mimicking a Colon Tumor: A Diagnostic Dilemma

A mesenteric solid tumor with unusual features in a young male: A case report

Leiomyomatosis peritonealis disseminata in postmenopausal women: a case report with review of literature

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