Primary mesenchymal chondrosarcoma of the breast

Padua, Michelle De; Bhandari, Tarun

doi:10.4103/0377-4929.44979

Cited by 6 publications

(2 citation statements)

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“…8 Based on this information, the extrapolated incidence is less than 215 cases per year in the United States. Although the literature contains many case reports 5,[9][10][11][12][13][14][15][16][17][18][19][20] and several case series, 2,3,4,[21][22][23][24][25][26] mesenchymal chondrosarcoma remains poorly understood, and consensus has not been reached on optimal management of the disease. The only consistently described features of mesenchymal chondrosarcoma are the unique, biphasic histology and the poor prognosis (see Table 1), despite variable lengths of disease-free survival.…”

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confidence: 99%

Mesenchymal Chondrosarcoma: Clinicopathologic Study of 20 Cases

Shakked¹,

Geller²,

Görlick³

et al. 2012

Archives of Pathology &Amp; Laboratory Medicine

112

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Mesenchymal chondrosarcoma presents multiple challenges. Diagnostic pitfalls include inadequate biopsy samples, which may result in sample error. Sox9 has been proposed as a unique marker for mesenchymal chondrosarcoma which may improve diagnostic specificity. Treatment and prognosis vary considerably. Patients who receive surgery and chemotherapy seem to fare better. Multicenter studies with higher sample numbers may improve our understanding of this malignancy.

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confidence: 99%

Mesenchymal Chondrosarcoma: Clinicopathologic Study of 20 Cases

Shakked¹,

Geller²,

Görlick³

et al. 2012

Archives of Pathology &Amp; Laboratory Medicine

112

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“…However, since it is important to remember that these neoplasms enter in differential diagnosis with metaplastic carcinoma and malignant phyllodes tumour [14], [15], we have preferred to perform sentinel lymph node biopsy in a preventive line in the eventuality of an incorrect temporary histological diagnosis (VACB): if this had happened, we would have had to operate again the patient.…”

Section: Discussionmentioning

confidence: 99%

Skin-nipple-sparing mastectomy: The first approach in primary myxoid chondrosarcoma of the breast

Militello

Zabbia

Mascolino

et al. 2017

International Journal of Surgery Case Reports

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The primary mammary chondrosarcoma corresponds to less than 0,5% of the mammary malignancies. For the period ranging from 1967 to 2014, only 18 cases were reported in the literature.A 41 year old woman found a hard nodule on her external right superior quadrant/axillary prolongation through breast self-examination. The vacuum-assisted core biopsy (VACB) revealed “high grade extra-skeletal myxoid chondrosarcoma”. A skin-nipple-sparing mastectomy with the insertion of a mammary expander was performed. A protocol of adjuvant radiotherapy was also indicated.Until 2013, the gold standard was the radical mastectomy. By 2014, there were two cases of conservative approach to quadrantectomy. To our knowledge, this represents the first case in the literature in which a skin-nipple-sparing mastectomy has been performed on a primitive mesenchymal neoplasm of the breast. Such an oncoplastic approach was performed considering the young age of the woman, to assure the surgical radicality and a better quality of life to the patient.

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