Primary meningococcal conjunctivitis and the need for prophylaxis in close contacts

Stansfield, Rosamund; Masterton, R G; Dale, Beverly A.; Fallon, R. J.

doi:10.1016/s0163-4453(94)90842-7

Cited by 13 publications

(8 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PMC is classically described as an acute or hyperacute purulent conjunctivitis that is accompanied by gross purulent exudate. The acute onset of unilateral purulent conjunctivitis in our patient was similar to that in most of the cases previously reported [1–4,7,8].…”

supporting

confidence: 89%

Primary meningococcal conjunctivitis

Orden

Martinez

Millán

et al. 2003

Clinical Microbiology and Infection

View full text Add to dashboard Cite

Neisseria meningitidis is an uncommon cause of acute bacterial conjunctivitis. One case of primary meningococcal conjunctivitis in a healthy 6-year-old boy is reported. The patient was initially treated with a topical instillation of polymyxin B, neomycin and gramicidin in ophthalmic solution, and this was followed by systemic rifampin once the diagnosis had been established. No ocular or systemic complications developed.

show abstract

supporting

confidence: 89%

Primary meningococcal conjunctivitis

Orden

Martinez

Millán

et al. 2003

Clinical Microbiology and Infection

View full text Add to dashboard Cite

show abstract

“…[2][3][4] Topical therapy alone is not sufficient to treat potential nasopharyngeal carriage, and the risk of developing invasive meningococcal disease is approximately 19 times greater for those receiving topical treatment alone compared to those also receiving systemic antibiotic treatment. 2 However, there is little published literature reporting on potential sources of PMC infection.…”

Section: Discussionmentioning

confidence: 99%

Primary meningococcal conjunctivitis: an unusual case of transmission by saliva

Dryden¹,

Rana²,

Pandey³

2016

Digit J Ophthalmol

View full text Add to dashboard Cite

SummaryA 49-year-old diabetic man presented with a 2-day history of a painful right eye associated with a purulent discharge. Prior to becoming symptomatic, he reported that someone spat at him, resulting in direct contact between the saliva and his affected eye. Gram stain revealed numerous leucocytes with Gram-negative diplococci, and culture yielded Neisseria meningitidis (serogroup C). There was no evidence of any systemic infection, and blood cultures were negative for any growth. He was treated for primary meningococcal conjunctivitis (PMC) with intensive topical antibiotic eyedrops as well as systemic antibiotics. One week after commencing treatment he remained systemically well and his symptoms had fully resolved.

show abstract

“…The Centers for Disease Control and Prevention guidelines do not recommend chemoprophylaxis of close contacts if the patient has no evidence of a sterile site infection, 28 although some experts recommend chemoprophylaxis of close contacts of patients with meningococcal conjunctivitis. 29 Despite variations in guidelines, data do not support widespread antibiotic chemoprophylaxis beyond close patient contacts (as described earlier) and this practice should be limited.…”

Section: Discussionmentioning

confidence: 99%