Primary melanoma of urinary bladder

Ahlen, H. van; Nicolas, Volkmar; Lenz, W.; Bockisch, Andreas; Boldth, Ilse; Vahlensieck, W

doi:10.1016/0090-4295(92)90414-r

Cited by 33 publications

(20 citation statements)

References 35 publications

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“…Squamous-cell carcinoma shows less of a propensity to metastasise to the genito-urinary tract. Though rare, primary small-cell carcinoma is well described in the bladder and prostate [90] and is normally histologically indistinguishable from a metastasis, although the presence of polytopic metastases or disproportionate hormonal effects may suggest disseminated disease (Fig. 4) [51,82].…”

Section: Histologymentioning

confidence: 98%

The significance of secondary neoplasms of the urinary and male genital tract

Bates

Baithun

2001

Virchows Arch

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Secondary neoplasms account for some 1.6-3.0% of solid malignancies encountered in surgical specimens from the genitourinary tract. At autopsy the proportion is higher, largely due to sampling bias. The peak incidence occurs around the seventh decade, and male and female incidences are approximately equal at all sites except the kidney, which shows a male preponderance owing to an excess of metastatic lung cancer. Adenocarcinomas are the most common histological type of secondary neoplasm and may be histologically and immunohistochemically indistinguishable from primary neoplasms arising from colonic-type epithelial metaplasia. Seeding of tumour along the urinary passages does not appear to be a significant mechanism of metastasis, and spread from one part of the genitourinary tract to another is uncommon. Clinical information and ancillary investigations are more helpful than special histological techniques in differential diagnosis.

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Section: Histologymentioning

confidence: 98%

The significance of secondary neoplasms of the urinary and male genital tract

Bates

Baithun

2001

Virchows Arch

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“…1,[2][3][4][5][6][7][8][9] In our case, the pigment was very scant, similar to what had been found in the case of Ahlen and colleagues. 11 In such cases, immunohistochemical study is required. The immunohistochemical markers S-100 protein and HMB-45 antigen have become an important component of diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Malignant melanoma of the bladder: A case report

Sayar

Erdoğan

Adamhasan

et al. 2014

CUAJ

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Cite as: Can Urol Assoc J 2014;8(1-2):e54-6. http://dx.doi.org/10.5489/cuaj.1242 Published online January 14, 2014. AbstractPrimary malignant melanoma of the bladder is very rare. Rather than being a primary lesion, malignant melanomas of the bladder are more commonly metastatic lesions. The histopathological appearance largely does not differ from that of melanoma at other body sites. It is often difficult to discriminate whether a bladder melanoma is primary or metastatic. Therefore, a careful review of histological features and performing necessary immunohistochemical staining procedures for S-100 protein and HMB-45 are very important in achieving a correct diagnosis. We report a case of hypomelanotic malignant melanoma of the bladder. Despite the variety of therapies available for primary melanomas of the bladder, the prognosis is still poor.

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“…However, some experts believe that the performance of a radical cystectomy and dissection of the pelvic lymph nodes is the best curative measure [7]. A combination of radiation and immunotherapy with recombinant interferon-α2 has been suggested as an alternative to radical surgery in elderly patients [44].…”

Section: Melanoma Of the Urinary Tractmentioning

confidence: 99%

Primary Extracutaneous Malignant Melanoma: A Comprehensive Review with Emphasis on Treatment

et al. 2004

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Extracutaneous malignant melanomas (EMM) require special consideration in the field of oncology due to their rareness and – depending on the localization – the frequency of late diagnosis with consecutive poor prognosis. Only 4–5% of all primary melanomas do not arise from the skin. Most frequently they originate from the mucous membranes lining the respiratory, digestive, and genitourinary tracts or in the eyes as well as in the cerebral meninges. Extracutaneous melanomas are considered to be biologically more aggressive than cutaneous melanomas. The Clark level and Breslow index used for evaluation of cutaneous melanomas are not applicable to EMM and, at present, there are no consistent, internationally accepted therapy standards for this form of the disease. For this reason, this review focuses primarily on the literature pertaining to therapeutic strategies as well as epidemiologic, biological, and diagnostic aspects of this disease.

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Primary melanoma of urinary bladder

Cited by 33 publications

References 35 publications

The significance of secondary neoplasms of the urinary and male genital tract

The significance of secondary neoplasms of the urinary and male genital tract

Malignant melanoma of the bladder: A case report

Primary Extracutaneous Malignant Melanoma: A Comprehensive Review with Emphasis on Treatment

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