Primary mediastinal dedifferentiated liposarcoma resected by lateral thoracotomy with video-assisted thoracoscopic surgery

Hamanaka, Kazutoshi; Ohashi, Masahiko; Nakamura, Toshitsugu

doi:10.1093/jscr/rjv163

Cited by 13 publications

(12 citation statements)

References 6 publications

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“…There have been a number of case reports regarding mediastinal dedifferentiated liposarcoma;1, 2, 3, 6, 7, 8, 9 however, few reports refer to long‐term prognosis. Coulibaly et al .…”

Section: Discussionmentioning

confidence: 99%

“…Based on the previous reports included in our review, complete surgical resection is the best method to cure mediastinal dedifferentiated liposarcoma 1, 3, 4, 5, 6, 7, 8, 9. En bloc resection should be attempted in such cases if possible.…”

Section: Discussionmentioning

confidence: 99%

“…Liposarcoma commonly occurs in the retroperitoneum or thigh, while primary mediastinal liposarcoma is rare and only a few cases have been reported to date 1, 2, 3, 4, 5, 6, 7, 8, 9. Liposarcoma has been subclassified histologically into well‐differentiated, myxoid, pleomorphic, and dedifferentiated types according to the 2012 National Comprehensive Cancer Network classification of liposarcoma 6.…”

Section: Introductionmentioning

confidence: 99%

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Primary mediastinal dedifferentiated liposarcoma: Five case reports and a review

et al. 2018

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BackgroundLiposarcoma has been subclassified histologically into well‐differentiated, myxoid, pleomorphic, and dedifferentiated types. The dedifferentiated type generally shows poorer prognosis than the well‐differentiated type. Because of its rarity, the clinicopathological features and clinical outcomes of primary mediastinal dedifferentiated liposarcoma remain unclear.MethodsFive patients with primary mediastinal dedifferentiated liposarcoma were treated at Shinshu University Hospital between January 2012 and August 2017. We investigated the clinical characteristics, including age, gender, radiographic findings, pathological status, and clinical and treatment outcomes.ResultsFour of the five patients initially underwent radical surgical resection. One patient was disease‐free after surgery, but the remaining three patients developed local recurrence in the mediastinum after surgical resection. Two of these patients underwent repeat surgical resection, resulting in long survival (60 and 40 months, respectively), while the other underwent proton beam therapy and showed no evidence of recurrence as of 17 months after treatment. The remaining patient was treated with chemotherapy using doxorubicin because of advanced inoperable disease, but failed to show a response and died within a month of the initiation of chemotherapy. Although the maximum standardized uptake values on fluorodeoxyglucose‐computed tomography were relatively low, there was a slight positive relation between these values and the Ki‐67‐positive ratio in the tumor.ConclusionAggressive treatment by surgical resection should be considered for mediastinal dedifferentiated liposarcoma, even in cases with local recurrence.

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“…There have been a number of case reports regarding mediastinal dedifferentiated liposarcoma;1, 2, 3, 6, 7, 8, 9 however, few reports refer to long‐term prognosis. Coulibaly et al .…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Primary mediastinal dedifferentiated liposarcoma: Five case reports and a review

et al. 2018

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“…It tends to involve the important mediastinal structures including esophagus, vessels, pericardium, etc. A standard median sternotomy or posterolateral thoracotomy is the most common surgical approaches [2, 4, 5]. In order to obtain a complete removal of the tumor, adjacent organs, such as the superior vena cava and phrenic nerve, must be mobilized.…”

Section: Discussionmentioning

confidence: 99%

Resection of giant mediastinal liposarcoma via ‘⊣ shape’ incision

Huang

Jiang

2017

J. surg. case rep.

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Primary mediastinal liposarcomas are extremely rare conditions often resected through standard median sternotomy or lateral thoracotomy. However, the management of a very huge mediastinal tumor involving hemithorax through these two common surgical approaches is always challenging. Herein, we report a case of applying median sternotomy with a sternum transection plus a right fourth intercostal thoracotomy (‘⊣ shape’ incision) to resect a giant primary anterior mediastinal liposarcoma extending into the whole right thorax. The final pathological diagnosis was a well-differentiated liposarcoma. The patient experienced an uneventful recovery. The ‘⊣ shape’ incision is a good backup for the extension of standard median sternotomy and provides a better exposure for both mediastinum and hemithorax.

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“…A few previous reports have presented the imaging findings of mediastinal dedifferentiated liposarcomas ( 1 , 2 ). We herein report a surgically resected case of dedifferentiated liposarcoma occurring in the right pulmonary hilum in a 47-year-old asymptomatic man.…”

mentioning

confidence: 99%