Primary malignant melanoma of the parotid gland: A case report and review of the literature

Chaouki, Anass; Berrada, Omar; Najib, Zouhair; Oukessou, Youssef; Abada, R.; Rouadi, Sami; Roubal, M.; Mahtar, M.

doi:10.1016/j.amsu.2020.11.085

Cited by 5 publications

(1 citation statement)

References 18 publications

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“…Other cases [36][37][38][39][40][41][42] were adequately studied and fully fulfilled selection criteria [19] of primary melanoma of salivary glands. They are presented in Tables 2 and 3.…”

Section: Discussionmentioning

confidence: 99%

Is Primary Poorly Differentiated Sarcomatoid Malignancy of the Parotid Gland Sarcomatoid Undifferentiated/Dedifferentiated Melanoma? Report of Three Unusual Cases Diagnosed by Fine-Needle Aspiration Combined with Histological, Immunohistochemical, and Molecular Analyses

Klijanienko,

Masliah-Planchon,

Choussy

et al. 2024

Acta Cytologica

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Introduction: Poorly differentiated primary sarcomatoid parotid malignancies are extremely rare. These tumors have not been consistently studied by morphology, immunohistochemistry, or molecular techniques. Case Presentation: We report three unusual cases of parotid gland poorly-differentiated sarcomatoid malignancy investigated by fine-needle aspiration and studied histologically, by immunohistochemistry and molecular investigations. Aspirates showed poorly specific polymorphous sarcomatoid malignancy in all cases. Histologically, all cases were polymorphous high-grade malignancies, and additionally, one case showed epithelial structures and was finally classified as salivary carcinosarcoma. Immunohistochemistry showed classical melanocytic markers negativity but positivity for PRAME, CD10, and WT1 in all three tumors and for CD56 in two tumors, which can potentially be supportive of melanocytic origin. Although not entirely specific, molecular characterization also suggested the melanocytic lineage of these tumors. Conclusion: Although rare, primary malignant melanoma of salivary gland was already described, but undifferentiated/dedifferentiated amelanotic forms are unknown in this localization up today. Further case reports of similar presentations are required to confirm the unequivocal primary origin of these obscure neoplasms in the parotid gland.

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“…Other cases [36][37][38][39][40][41][42] were adequately studied and fully fulfilled selection criteria [19] of primary melanoma of salivary glands. They are presented in Tables 2 and 3.…”

Section: Discussionmentioning

confidence: 99%

Is Primary Poorly Differentiated Sarcomatoid Malignancy of the Parotid Gland Sarcomatoid Undifferentiated/Dedifferentiated Melanoma? Report of Three Unusual Cases Diagnosed by Fine-Needle Aspiration Combined with Histological, Immunohistochemical, and Molecular Analyses

Klijanienko,

Masliah-Planchon,

Choussy

et al. 2024

Acta Cytologica

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Primary Malignant Melanoma in the Parotid Gland: A Case Report and Literature Review

Yan,

Duan,

et al. 2024

Ear Nose Throat J

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Primary melanoma of the parotid gland is an extremely rare and challenging tumor with a poor prognosis, and its ultrasonic characteristics have yet to be reported. This article presents a case of a 77-year-old man with a left parotid mass that was confirmed as a melanoma following surgery. The ultrasonic features of melanoma were examined in detail, with a particular focus on their diagnostic value. Furthermore, we summarized the clinical characteristics, treatment options, and outcomes associated with primary melanoma of the parotid gland based on a thorough analysis of the available literature.

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A Rare Entity: Primary Malignant Melanoma of the Parotid Gland

Gozgec,

Sakat,

Guven

et al. 2024

Ear Nose Throat J

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Primary malignant melanoma of the parotid gland: A case report and review of the literature

Cited by 5 publications

References 18 publications

Is Primary Poorly Differentiated Sarcomatoid Malignancy of the Parotid Gland Sarcomatoid Undifferentiated/Dedifferentiated Melanoma? Report of Three Unusual Cases Diagnosed by Fine-Needle Aspiration Combined with Histological, Immunohistochemical, and Molecular Analyses

Is Primary Poorly Differentiated Sarcomatoid Malignancy of the Parotid Gland Sarcomatoid Undifferentiated/Dedifferentiated Melanoma? Report of Three Unusual Cases Diagnosed by Fine-Needle Aspiration Combined with Histological, Immunohistochemical, and Molecular Analyses

Primary Malignant Melanoma in the Parotid Gland: A Case Report and Literature Review

A Rare Entity: Primary Malignant Melanoma of the Parotid Gland

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