Primary Malignant Lymphoma of the Bladder Diagnosed by Transurethral Bladder Tumor Resection: A Case Report

Mucosa-associated lymphoid tissue lymphoma of the bladder: Case report

“…Since 1990, chemotherapy or radiation therapy, which can preserve the bladder, has become the mainstay of treatment. 1 …”

“…NHL occurs in various organs, and the most common sites of NHL are the tonsil (24.8%), stomach (13.4%), and pharynx (11.6%). 1 NHL can also occur in the mucosa-associated lymphoid tissue (MALT). Primary malignant lymphoma of the bladder is an extremely rare disease, accounting for 0.2% of extra nodal malignant lymphomas and 0.2% of primary bladder tumors.…”

A Case of Mucosa-Associated Lymphoid Tissue Lymphoma of the Bladder: An Extremely Rare Presentation

“…Given the rarity of this tumor, a limited literature review is present and there is no standard protocol for the management of the tumor. Treatment approaches are variable, and patients were treated with approaches including surgical excision of the tumor, chemotherapy, radiation, antibiotics, or combined modality in different cases with complete remission [ 6 ]. A clear-cut consensus is not available about a standard treatment plan for such patients and the efficacy of one treatment over the other hasn't been determined yet.…”

A rare cause for hematuria: Lymphoma of the urinary bladder

“…[2] Since there is no consensus on the optimal therapy, either of radiation, chemotherapy, targeted therapy, or a combination have been attempted and are successful in attaining remission. A few patients were treated with local therapy only, such as transurethral resection of bladder tumor [5] and diathermy. There was one patient who attained CR with Helicobacter pylori eradication therapy alone, [6] while another patient was treated exclusively with rituximab.…”

“…Age (years)/gender Presenting symptoms Treatment Outcome D'Souza et al [1] 56/male Hematuria, clot retention TURBT CR at 3 years Combaz and Kuhn [2] 67/female Recurrent cystitis, asthenia Rituximab (375 mg/m 2 weekly, 4 weeks) CR at 3 years Isono et al, 2018 [3] 77/female Frequency, hematuria, cystitis Radiotherapy (30.6 Gy in 17 fractions) CR at 5 years Ozawa et al [5] 72/female Thrombocytosis TURBT CR at 13 months Matsuda et al [7] 78/female Refractory cystitis and renal dysfunction Rituximab × 4 cycles PR Haddad-Lacle et al, 2014 [8] 54/male Low back pain Radiotherapy (30.6 Gy in 17 fractions) No recurrence at 3 years Chen et al [9] 63/female Gross hematuria and urethral caruncle Radiotherapy to bladder (36 Gy) and pelvic and inguinal lymph nodes (45 Gy)…”