Primary malignant lymphoma of the parotid gland

Abstract

Lymphoma of the salivary gland accounts for 5% of cases of extranodal lymphoma and 10% of malignant salivary gland tumors. Most primary salivary gland lymphomas are B marginal zone lymphomas arising on a background of sialadenitis associated with an autoimmune disorder such as Sjorgen's syndrome. This report describes a case of primary B-cell lymphoma arising in the parotid gland in a middle-aged female, which was not associated with an autoimmune disorder. Immunohistochemistry studies confirmed the clonal B-cell nature of the tumor. This case highlights the fact that B-cell lymphoma in the salivary gland can go unrecognized due to its non-specific symptoms and requires immunohistochemistry studies for confirmation. We present this case for its rarity.

T-Cell Lymphoma Presenting with Auricular and Parotid Gland Involvement

“…Malignant lymphomas arising from the salivary glands are also uncommon, accounting for approximately 5% of extranodal lymphomas, and the majority of them are of B-cell lineage. Primary salivary gland T-cell lymphomas are extremely rare [ 3 , 4 , 5 ].…”