Primary lymphoma of the uterine cervix: a clinicopathologic study of 13 cases with review of additional 54 cases in the literature

Weng, Xin; Huang, Mayan; Zhang, Meng; Yang, Yue; Liu, Xia; Huang, Yuhua

doi:10.1007/s00428-022-03436-y

Cited by 3 publications

(1 citation statement)

References 36 publications

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“…Primary uterine and vaginal lymphoma usually manifests as abnormal vaginal bleeding after menopause, which may be related to the changes in hormone levels in postmenopausal women, the endometrial loss of the support of periodic changes in hormones and excessive proliferation. 11 The macroscopic appearance is also easily confused with squamous cell carcinoma. The age of the patient with uterine lymphoma is related to the pathological type, with diffuse large B-cell lymphoma being more likely to occur between 35 and 45 years old; and follicular lymphoma usually occurs in women >50 years old.…”

Section: Discussionmentioning

confidence: 99%

A rare case report of primary uterine and vaginal lymphoma in the elderly

Gao

Wang

et al. 2023

J Int Med Res

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Uterine lymphoma is rare and usually occurs in middle-aged women. The clinical symptoms lack any specific characteristics. Imaging characteristics usually include uterine enlargement with density and uniform signal soft tissue masses. Magnetic resonance T2 weighted imaging, enhanced scanning, diffusion weighted imaging and apparent diffusion coefficient values have certain characteristics. The gold standard for diagnosis remains a pathological examination of a biopsy specimen. The special feature of this current case was that the uterine lymphoma occurred in an 83-year-old female patient that presented with a pelvic mass for more than 1 month. Based on the imaging findings, a primary uterine lymphoma was considered, but her advanced age of onset did not match the disease. After pathological confirmation, the patient was diagnosed with uterine lymphoma and she received eight cycles of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone) plus local radiotherapy for the large masses. The patients achieved good results. Follow-up enhanced computed tomography imaging showed that the uterine volume had significantly reduced compared with before treatment. The diagnosis of elderly patients with uterine lymphoma can provide a more accurate plan for subsequent treatment.

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Section: Discussionmentioning

confidence: 99%