Primary lymphoma of the head and neck: two case reports and review of the literature

Essâdi, Ismail; Ismaili, Nabil; Tazi, Elmehdi; Elmajjaoui, Sanaa; Saidi, A; Ichou, Mohammed; Errihani, Hassan

doi:10.1186/1757-1626-1-426

Cited by 23 publications

(25 citation statements)

References 12 publications

(22 reference statements)

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“…A rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone regimen is considered to be the standard treatment for patients with advanced diffuse large B-cell lymphoma. [7] The prognosis for primary prostatic lymphoma is uncertain, due to the rarity of the disease. It has been suggested that the prognosis of nodal lymphomas may be similar to that of extranodal lymphomas.…”

Section: Discussionmentioning

confidence: 99%

Primary non-Hodgkin follicular lymphoma of the prostate: A case report

Görgel

Şefik

Olğunelma

et al. 2014

Turkish Journal of Urology

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Primary lymphoma of the prostate is a rare condition, representing 0.09% of prostatic malignancies. The clinical presentation of malignant lymphoma of the prostate is difficult to distinguish from other prostatic diseases. Systemic symptoms are rare. Treatments include surgery, chemotherapy and/or radiotherapy. We report a case of primary lymphoma of the prostate in a male patient who presented with lower urinary tract symptoms.

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Section: Discussionmentioning

confidence: 99%

Primary non-Hodgkin follicular lymphoma of the prostate: A case report

Görgel

Şefik

Olğunelma

et al. 2014

Turkish Journal of Urology

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“…DLBCL, follicular lymphoma, and Burkitt lymphoma), [16] and DLBCL and EBV+ NK/T-cell lymphomas of the nose, paranasal sinuses, and oropharynx (Table 27-5) [17]. Secondary spread of follicular lymphoma into the salivary glands from adjacent lymph nodes is also common.…”

Section: Lymphomas Of the Head And Neck And Thyroidmentioning

confidence: 99%

Extranodal Lymphomas and Tumors of the Thymus

Stewart

Manning

Jones

2009

Neoplastic Hematopathology

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Abstract/Scope of ChapterThis chapter provides an overview of lymphomas and related tumors presenting at extranodal locations. Commonalities and differences in the approach to diagnosis, staging, and their pathogenesis are summarized. Intrinsic tumors of the thymus are also discussed. Keywords Overview of Extranodal Lymphomas General FeaturesThe definition of an extranodal lymphoma is usually one in which the presenting tissue site is the location of primary involvement for at least 3-6 months following diagnosis. However, some extranodal lymphomas show systemic spread much more rapidly (e.g. those in the spleen or tonsils), whereas lymphomas at other sites (e.g. the skin or stomach) can remain localized for many years even without treatment. The general demographic features of extranodal lymphomas are similar to nodal cases, with median age in the fifth to sixth decade at diagnosis, except for those cases with antigen-driven or autoimmune etiology (e.g. MALT lymphomas), which usually present at a slightly younger age.The overall distribution of lymphomas at different extranodal sites is shown in Table 27-1. Several conclusions can be drawn: (1) there are major differences in the types of extranodal lymphomas arising in pediatric and adult patients;[1] (2) geographic differences are noted in the incidence of extranodal lymphomas related to their inciting causes; (3) lymphomas are rare in immune-privileged sites such as the central nervous system (CNS) and testes; and (4) although individual differences in histologic types occur at each site, diffuse large B-cell lymphoma (DLBCL) and marginal zone lymphoma of MALT type (MALT lymphoma) are the most common B-cell lymphomas at most extranodal sites in adult patients, with follicular lymphoma (FL) commonly involving any organ with secondary lymphoid tissue, including bowel mucosa. The most important insight into the development of lymphomas at extranodal sites was the observation that lymphomas sometimes develop from the nonneoplastic mucosa-associated lymphoid tissue (MALT) that arises in inflammatory states. The concept was first developed to explain the emergence of low-grade marginal zone B-cell lymphomas in the small intestine of patients with preceding bacterial infections, but Isaacson and colleagues [2] subsequently expanded the concept to explain the inflammatory-based histogenesis of MALT lymphomas at other extranodal sites . As summarized in Table 27-2, several additional B-cell and T-cell lymphomas have a clear association with preceding inflammatory states, such as mycosis fungoides (MF) arising out of chronic dermatitis ( Fig. 27-1b).Another driver of the extranodal localization of lymphoproliferative disorders is the recruitment of tumor lymphocytes to sites of ongoing inflammation or immune activation. This is particularly common in follicular lymphoma (FL), which homes to germinal centers at any tissue site, and in chronic lymphocytic leukemia/small lymphocyte lymphoma (CLL/SLL), which colonizes sites of preexisting inflammation. As a result, CLL i...

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“…They mainly involve lymph nodes, spleen and other non-hemopoietic tissues, with painless enlargement of lymph nodes being the most common presenting symptom. However, an important feature of NHL which distinguishes it from Hodgkin's disease is that NHL can arise in an extranodal site, either as a primary or occult lesion [1] [2].…”

Section: Introductionmentioning

confidence: 99%

“…Most NHLs arise in lymph nodes or other lymphatic tissues such as the spleen, Waldeyer's ring and thymus [2]. Involvement of extranodal organs is a common finding after staging investigation, however, about 25% -40% of NHL patients present with a primary extranodal lymphoma, and common presenting sites include gastrointestinal tract, pharynx, thyroid, lung, central nervous system, orbit, salivary glands and skin [3] [4].…”

Section: Introductionmentioning

confidence: 99%

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Advanced Primary Lymphoma of Oral Cavity: Report of a Case

Alirezaei¹,

Baharvand²,

Tavakoli³

et al. 2014

OJST

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Usually the oral manifestations of NHL are secondary to a more widespread involvement throughout the body, however, it can rarely present as a primary lesion in the oral cavity, having 0.1% -0.2% prevalence. In this paper we report a case of highly proliferative oral non-Hodgkin lymphoma which presented with very mild symptoms, but had a sudden and significant progression in less than two weeks with involvement of all four quadrants of the oral cavity.

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Primary lymphoma of the head and neck: two case reports and review of the literature

Cited by 23 publications

References 12 publications

Primary non-Hodgkin follicular lymphoma of the prostate: A case report

Primary non-Hodgkin follicular lymphoma of the prostate: A case report

Extranodal Lymphomas and Tumors of the Thymus

Advanced Primary Lymphoma of Oral Cavity: Report of a Case

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