Primary lymphoma of the appendix: A case report and review of the literature

Mucosa-associated lymphoid tissue lymphoma of the appendix stump: a case report

“…In most cases, appendicular lymphomas, like the rest of the appendix tumors, manifest with a picture of acute appendicitis, other less frequent symptoms are anorexia, weight loss, gastrointestinal bleeding and intussusception. 5,7 In In our case, the presentation agrees with the most frequent one described in the literature, a picture of acute appendicitis, the age of presentation is according to that reported in the literature, the sixth decade of life, however, the histological type found does not agree with the casuistry reported, since appendicular lymphomas appear in the population between the second and third decade of life. Surgical conduct in neoplasms of the cecal appendix is quite contradictory and there is still no agreement that allows to guide the surgeon on which is the ideal treatment, that is, in the case of appendicular A B tumors larger than 2 cm, tumors that infiltrate the mesoappendix, which compromise the cecum or that present a high mitotic index, it is necessary to perform right hemicolectomy with lymph node dissection, while other studies recommend that simple appendectomy with stump closure should be performed, reserving definitive treatment once the histopathological result is obtained.…”

“…Surgical conduct in neoplasms of the cecal appendix is quite contradictory and there is still no agreement that allows to guide the surgeon on which is the ideal treatment, that is, in the case of appendicular A B tumors larger than 2 cm, tumors that infiltrate the mesoappendix, which compromise the cecum or that present a high mitotic index, it is necessary to perform right hemicolectomy with lymph node dissection, while other studies recommend that simple appendectomy with stump closure should be performed, reserving definitive treatment once the histopathological result is obtained. 5,9,10 In the present case, it is striking that although at first the finding of a neoplasm or tumor in the inflamed appendix was not reported, later after a period of 3 weeks a significant tumor has developed, probably having the proliferative stimulus as surgical trauma, a fact that has not been described in the reviewed literature. It has been described that immunocompromised patients, especially HIV-positive patients, can present lymphomas of atypical location, so it is necessary to perform an ELISA and western-blot study as part of the diagnostic approach, said approach was performed in the present case, resulting positive for HIV infection.…”

“…It has been described that immunocompromised patients, especially HIV-positive patients, can present lymphomas of atypical location, so it is necessary to perform an ELISA and western-blot study as part of the diagnostic approach, said approach was performed in the present case, resulting positive for HIV infection. 5…”

“…The most common manifestation is acute appendicitis secondary to luminal obstruction. 1,5 The histopathological and immunohistochemical study is mandatory to make the diagnosis, it is necessary to rule out its origin elsewhere in the body. Cases have been reported in children, the most common of which is Burkitt's lymphoma, while in adults it is more common to find large cell non-Hodgkin lymphoma and immunophenotype B low-grade non-Hodgkin.…”

Burkitt Lymphoma of the Appendix Presenting With Acute Appendicitis and Acute Kidney Injury: A Case Report and Review of Literature

“…Diffuse enlargement of the appendix with thickening of its wall and periappendiceal tissue can be seen on imaging, representing a direct serosal extension of lymphomatous cells or a related inflammatory process. The diameter and size of the lymphomatous appendix on CT scan are usually >3 cm, which is larger than the expected size of non-tumor appendicitis [ 9 - 12 ]. However, in our case, the CT scan revealed no abdominal lymphadenopathy, and the appendix was not clearly visible.…”