Primary Liver Tumors in Pediatric Patients: Proper Imaging Technique for Diagnosis and Staging

Rozell, Joseph M.; Catanzano, Tara; Polansky, Stanley; Rakita, Dmitry; Fox, Lindsay

doi:10.1053/j.sult.2014.05.006

Cited by 13 publications

(7 citation statements)

References 16 publications

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“…Although a single-phase CT may have been sufficient, a contrastenhanced (gadoxetate disodium) MRI was performed because it was considered more sensitive (preferential binding of contrast to hepatocytes, resulting in improved soft tissue characterization), but also carried more risk. 9 The anesthetic challenges encountered with our previous patient were reinforced by a second case that involved a 6-month-old, 9.4-kg male with a right renal vein thrombosis and subsequent hypertension that required pharmacologic management. His abdominal ultrasound was suspicious for a persistent thrombus as his inferior vena cava distal to the hepatic veins showed no color flow on Doppler.…”

Section: Ch Allen Ging Case Smentioning

confidence: 90%

“…Because only short apneic periods were tolerated and repeated interventions were needed to resume adequate oxygenation, the length of the procedure (70 minutes) and exposure time to anesthesia were prolonged. Although a single‐phase CT may have been sufficient, a contrast‐enhanced (gadoxetate disodium) MRI was performed because it was considered more sensitive (preferential binding of contrast to hepatocytes, resulting in improved soft tissue characterization), but also carried more risk …”

Section: Challenging Casesmentioning

confidence: 99%

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Changing the paradigm for diagnostic MRI in pediatrics: Don't hold your breath

Masaracchia

Tsapakos

McNulty

et al. 2017

Pediatric Anesthesia

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Increasingly complex pediatric patients and improvements in technology warrant reevaluation of the risk associated with anesthesia for diagnostic imaging. Although magnetic resonance imaging is the imaging modality of choice for children given the potentially harmful effects of computerized tomography-associated ionizing radiation, we dare to suggest that certain patients would benefit from the liberalization of our current standard. Incorporating the use of newer computerized tomography technology may improve safety for those that are already at higher risk for adverse events. Furthermore, magnetic resonance imaging is not risk-free-what is often overlooked is the need for controlled ventilation and breath-holding to minimize motion artifact. As physicians at the forefront of the development and sustainability of the perioperative surgical home, anesthesiologists must work to not only optimize patients preoperatively but should also act as gatekeepers for procedural safety.

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Section: Ch Allen Ging Case Smentioning

confidence: 90%

Section: Challenging Casesmentioning

confidence: 99%

Changing the paradigm for diagnostic MRI in pediatrics: Don't hold your breath

Masaracchia

Tsapakos

McNulty

et al. 2017

Pediatric Anesthesia

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“…Bei großen (Riesen-)Hämangiomen (Durchmesser > 5 cm) kommt es häufig zu zentralen Hämorrhagien, Nekrose und Thrombose, so dass die diagnostische Einordnung anhand der Bildgebung schwierig sein kann, insbesondere, wenn eine sonstige Grunderkrankung vorliegt. Sie sind bei Kindern selten, und das typische Irisblendenphänomen im CEUS ermöglicht in der Regel die Diagnose, so dass keine zusätzliche MRT erforderlich ist [10,13,20].…”

Section: Hämangiomunclassified

Bildgebung von Lebertumoren im Kindes- und Jugendalter

Tschauner

Riccabona

2021

Radiologe

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Zusammenfassung Hintergrund Kindliche Lebertumoren sind relativ selten, aber die Kenntnisse über ihre bildgebende Diagnostik nicht weniger wichtig. Fragestellung Häufigkeit und Bildmorphologie benigner und maligner Raumforderungen der Leber im Kindesalter. Material und Methode Aufbereitung der einschlägigen Originalarbeiten, Übersichtsarbeiten und Expertenempfehlungen betreffend die Bildgebung kindlicher Lebertumoren. Ergebnisse Die häufigsten bösartigen Lebertumoren sind das meist bei Kleinkindern auftretende Hepatoblastom sowie in manchen Regionen auch das hepatozelluläre Karzinom. Ihre Bildmorphologie ist im Gegensatz zu manchen benignen Raumforderungen, wie beispielsweise der fokalen nodulären Hyperplasie, simplen Zysten oder Steatosearealen, wenig charakteristisch. Radiologisch kommen üblicherweise die Sonographie und die Magnetresonanztomographie (MRT) zum Einsatz. Beide Methoden profitieren von einer intravenösen Kontrastmittelgabe. Schlussfolgerung Kindliche Lebertumoren weisen ein breites morphologisches Spektrum auf. Manche Entitäten lassen sich mittels Bildgebung charakterisieren, manche benötigen eine multimodale Bildgebung oder eine histologische Begutachtung. Neben den bildmorphologischen Kriterien spielen insbesondere auch Alter, Laborparameter und Anamnese eine wichtige Rolle in der Diagnosefindung.

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“…The liver lesions most commonly seen in the neonatal period include hemangioma, mesenchymal hamartoma, and hepatoblastoma (8,52…”

Section: Tumorsmentioning

confidence: 99%

Hepatic Imaging in Neonates and Young Infants: State of the Art

et al. 2017

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Neonatal liver disease is an important source of morbidity in the pediatric population. The manifestation of liver disease in young infants may be different than in older patients, and there are a number of diagnoses that are unique to this age group. Familiarity with these entities is important as imaging plays a key role in the diagnostic workup, and prompt diagnosis is necessary to prevent complications. This article reviews the spectrum of liver pathologies that can manifest in the first 6 months of life and is intended to educate the general radiologist who may be faced with interpretation of neonatal liver imaging. Categories of disease that will be reviewed include cholestatic diseases, tumors, vascular anomalies, and acquired diseases. The authors will also review optimization of ultrasonography (US) and magnetic resonance imaging of the liver and present a systematic method for interpretation of neonatal liver US findings in the context of clinical and laboratory findings. RSNA, 2017.

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Primary Liver Tumors in Pediatric Patients: Proper Imaging Technique for Diagnosis and Staging

Cited by 13 publications

References 16 publications

Changing the paradigm for diagnostic MRI in pediatrics: Don't hold your breath

Changing the paradigm for diagnostic MRI in pediatrics: Don't hold your breath

Bildgebung von Lebertumoren im Kindes- und Jugendalter

Hepatic Imaging in Neonates and Young Infants: State of the Art

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