Primary Liver Lymphoma: A Case Report and Literature Review

Bourhafour, Mouna; Wafae, Allam; Mrabti, Hind; Errihani, Hassan

doi:10.4236/jct.2011.25098

Cited by 6 publications

(6 citation statements)

References 7 publications

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“…The primary hepatic lymphoma presents with hepatic invasive behavior, and may present diffuse involvement. It is a very rare disease of unknown etiology, although studies points to be related to viral infection with HVB or HVC [1], but in this case there were negative.…”

Section: Discussionmentioning

confidence: 67%

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Primary Liver Large B-Cell Lymphoma: A Rare Diagnosis

Rocha¹,

Lopes²,

Cruz³

et al. 2015

OJBD

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Primary liver lymphoma is extremely rare, in most of cases it is a B cell lymphoma. Usually the diagnosis is made in middle-aged individuals and most of them have a relatively short life expectancy. In this article, the authors present a case report of a 75-year-old woman with symptoms of three weeks of evolution of diffuse abdominal pain, asthenia and anorexia. The analysis showed cyto cholestasis and the radiological image with lush hepatomegaly because of a large hepatic mass. The patient started chemotherapy and actually is well twenty months after the end of the chemotherapy.

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Section: Discussionmentioning

confidence: 67%

“…Primary liver lymphoma has high rarity diagnosis [1]- [6], corresponding to less than "1%" of all lymphomas [7]- [9]. It acounts approximately for "0.4%" [10] [11] of the extranodal non-Hodgkin lymphomas and approximately "0.01%" to "0.06%" [1] [2] [6] [7] [12] of the non-Hodgkin lymphomas.…”

Section: Introductionmentioning

confidence: 99%

Primary Liver Large B-Cell Lymphoma: A Rare Diagnosis

Rocha¹,

Lopes²,

Cruz³

et al. 2015

OJBD

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“…Los tumores neuroendocrinos primarios hepáticos fueron las NHPM no HCC no CC más frecuentes de nuestra serie. De los diez pacientes con confirmación histológica de tumor neuroendocrino hepático, observamos una relación 1:1 según sexo, edad entre 48 y 86 años, lo cual es concordante con lo reportado [2][3][4][5][6] , aunque en algunas series se demuestra una mayor frecuencia en mujeres. Todos nuestros casos fueron no funcionantes, siendo la manifestación más frecuente (50% de los casos) presencia de una masa abdominal.…”

Section: Discussionunclassified

“…El linfoma primario del hígado fue la segunda causa más frecuente de la serie con 24% de los casos. Según la literatura, este tipo de tumor se presenta más frecuentemente en contexto de inmunosupresión [2][3][4][5][6] . Para el diagnóstico definitivo en todos los casos fue necesaria la biopsia de la lesión, siendo inespecíficos clínica, laboratorio e imágenes, como ha sido reportado anteriormente 2-6 .…”

Section: Discussionunclassified

Tumores hepáticos primarios malignos no hepatocarcinoma ni colangiocarcinoma

et al. 2019

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Primary malignant hepatic tumors other than hepatocarcinoma or cholangiocarcinoma. A series of casesBackground: There are several types of primary malignant hepatic tumors (PMHT) other than hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC): they are infrequent and poorly known. Imaging studies could help characterize the lesions and may guide the diagnosis. However, the definitive diagnosis of PMHT is made by pathology. Aim: To review a registry of liver biopsies performed to diagnose hepatic tumors. Patients and Methods: Review of a pathology registry of liver biopsies performed for the diagnosis of liver tumors. Among these, 25 patients aged 57 ± 17 years, 60% males, in whom a liver tumor other than a HCC or CC was diagnosed, were selected for review. The medical records of these patients were reviewed to register their clinical characteristics, imaging and the pathological diagnosis performed during surgery and/ or with the percutaneous liver biopsy. Results: Ten patients (40%) had neuroendocrine tumors, six (24%) had a lymphoma and four (16%) had hepatic hemangioendothelioma. Angiosarcoma and sarcomatoid carcinoma were diagnosed in one patient each. In 22 patients (88%), neither clinical features nor imaging studies gave the correct diagnosis. Four patients (16%) had chronic liver disease. The most frequent symptoms were weight loss in 28% and abdominal pain in 24%. Conclusions: The most common PMHT other than HCC and CC were neuroendocrine tumors and lymphomas. Imaging or clinical features were not helpful to reach the correct diagnosis. (Rev Med Chile 2019; 147: 751-754)

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“…PHL is liver-derived ENL without other organ involvement. PHL constitutes 0.4% of ENLs (45). A total of 2 cases were diagnosed as PHL in our institute.…”

Section: Pulmonarymentioning

confidence: 92%

Clinicopathological Features of Extranodal Lymphomas

Coşkun

Nazlioglu

Büyükuysal

2021

Konuralp Tıp Dergisi

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Objective: In this study, we aimed to evaluate the localization and histopathological diagnosis, and clinicopathologic characteristics of primary extranodal lymphomas. Methods: The pathology reports between 2001 and 2015 in the archives of Uludag University Faculty of Medicine Pathology Department were reviewed and all cases with an extranodal lymphoma diagnosis were analyzed. The information about the diagnosis, tumor localization, symptoms at presentation, presence of B symptoms, lymphocytosis and anemia, chronic infection and chronic disease and concomitant secondary malignancy, tumor diameter, the involvement of another extranodal organ, lymph node, bone marrow, spleen, liver, stage of the disease, serum B2 microglobulin, LDH, albumin levels, sedimentation rate were documented. The localization, histopathological types, age groups, male/female ratios in cases of primary extranodal lymphoma were evaluated. Results: Total sum of 1743 patients were diagnosed with lymphoma. 480 (%27,53) of these cases were extranodal lymphomas. The most commonly encountered locations of extranodal lymphomas were the skin and the gastrointestinal system. There were 226 primary extranodal skin, 90 gastrointestinal system, 44 central nervous system, 8 genitourinary system, 50 head and neck, 18 musculoskeletal system and soft tissue, 9 mediastinum, 3 bronchus, 10 orbital, 2 liver, 6 pancreas, 4 omentum, 8 endocrine system, and 2 breast located cases. 237 of the primary extranodal lymphomas from our work were mature T/NK celled neoplasias. There were 250 patients with mature B cell lymphoma, 5 cases of Hodgkin lymphoma, and 5 cases of precursor lymphoid neoplasia. Conclusions: The data from our series were coherent with the literature. Due to the small number of cases with some localization and some histopathological diagnosis, no significant results could be reached about these entities.

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Primary Liver Lymphoma: A Case Report and Literature Review

Abstract: ABSTRACT

Cited by 6 publications

References 7 publications

Primary Liver Large B-Cell Lymphoma: A Rare Diagnosis

Primary Liver Large B-Cell Lymphoma: A Rare Diagnosis

Tumores hepáticos primarios malignos no hepatocarcinoma ni colangiocarcinoma

Clinicopathological Features of Extranodal Lymphomas

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