Primary leiomyosarcoma of the great saphenous vein: A case report

Tresgallo-Parés, Ruben; Virgilio-Salgado, Lucas De; Torres-Lugo, Norberto J.; Asenjo-Molina, Natalia A.; Ramírez, Norman; Bibiloni-Rodríguez, Juan

doi:10.1016/j.ijscr.2021.106565

Cited by 6 publications

(3 citation statements)

References 31 publications

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“…The IVC is the most usually damaged vascular structure (35-60% of the cases). Nonetheless, several occurrences of GSV in the lower extremities have been observed (Tresgallo-Parés et al, 2021). Adjuvant chemotherapy can be explored in high-risk patients to lower the risk of local recurrence and improve survival rates, even if it is not universally acknowledged as the standard therapeutic plan for the postoperative care of adult patients with LMS (Gamboa, Gronchi, & Cardona, 2020).…”

Section: Resultsmentioning

confidence: 99%

Acute Jejunal Leiomyosarcoma: A Rare Case Study

Essa Alfard

2023

Am. J. Med. Sci. Innov.

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The objective of this study is to describe a particular case example of small bowel leiomyosarcoma, which is characterized by an acute abdomen and signs and symptoms of intestinal obstruction. Sarcoma accounts for 1.2% of gastrointestinal malignancies. It can present as an asymptomatic mass or with constitutional symptoms like GI upset, melena, weight loss, fatigue, and rarely intussusception and bowel obstruction. Early diagnosis is difficult due to unspecified symptoms and the slow growth of the tumor. Surgical resection is still the preferred therapy. The case report was based on a 31-year-old gentleman hospitalized in the Emergency with severe abdominal aches, discomfort and nausea for 4 days. The patient had a significant unintentional weight loss for 1 month. A physical examination revealed epigastric and periumbilical tenderness. An immediate abdominal X-ray revealed several air-fluid levels, which indicate a minor intestinal obstruction in the core of the abdomen. A subsequent CT scan further noted an ileoileal intussusception with intestinal obstruction. The decision was taken to proceed with a crucial exploratory laparotomy, which reported a 4x5 cm tumor in the jejunum with several enlarged mesenteric lymph nodes. The histopathology report showed a high-grade leiomyosarcoma with confirmatory immunological staining.

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Section: Resultsmentioning

confidence: 99%

Acute Jejunal Leiomyosarcoma: A Rare Case Study

Essa Alfard

2023

Am. J. Med. Sci. Innov.

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“…When diagnostic confirmation is necessary, direct tissue evaluation should be performed. 18 This can be done through needle or core biopsies, followed by an open biopsy, if needed. A histologic diagnosis is crucial in determining the extent of resection, which can help in performing single-stage surgery with wide local excision instead of multiple surgeries.…”

Section: Discussionmentioning

confidence: 99%

Great saphenous vein leiomyosarcoma mimicking thrombosed aneurysm: A case report and review of the literature

Atieh,

Allaw,

Ashouri

et al. 2024

Journal of Vascular Surgery Cases, Innovations and Techniques

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“…It is 5 times more likely to occur in veins than in arteries, with 30% of all the cases attacking the great saphenous vein (GSV). Because of its asymptomatic nature, leiomyosarcoma diagnosis and treatment are often delayed and have poor prognosis [ 3 – 5 ]. LMS can originate from any smooth muscle, including the tunica media of blood vessels, and thus can be found in any part of the body that contains these structures [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Multifocal Sarcoma Mimicking Superficial Vein Thrombosis of the Leg: A Case Report

Dziekiewicz

Obara

Makowski³

2022

Am J Case Rep

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Patient: Female, 61-year-old Final Diagnosis: Leiomyosarcoma Symptoms: Pain • redness • tenderness • warmth Medication: — Clinical Procedure: Excision of tumor Specialty: Surgery Objective: Unusual clinical course Background: Leiomyosarcoma is a common tumor found in soft tissue. In relation to the vascular system, leiomyosarcoma appears as the most common malignancy characterized by poor prognosis. Leiomyosarcomas of the leg large vessels often occur late, and their appearance can imitate vein thrombosis with symptoms such as soft tissue swelling or mild pain, and can be misdiagnosed. Peripheral vascular leiomyosarcomas are rare. Especially leiomyosarcomas of the great saphenous vein are uncommon. The tumors develop on the media basis and grow from endovascular to exovascular order. Distant metastasis can be identified and worsen prognosis. Case Report: We present a case of a 61-year-old female patient with varicose vein disease complicated by recurrent superficial vein thrombosis. After 2 months of conservative treatment, while waiting for admission to the department of surgery, she developed additional symptoms. Clinical examination on the day of admission revealed several tumors along and near the great saphenous vein on the left limb below the knee. The diagnosis of leiomyosarcoma was confirmed after the surgery, involving excision of the saphenous vein, including tumors formed on its course. Preoperative clinical and ultrasound findings did not suggest malignancy. Conclusions: Leiomyosarcoma of the great saphenous vein is an extraordinarily rare tumor originating from the middle layer of the vessel, mimicking unspecific symptoms and complicating and delaying diagnosis. In every case of vascular or perivascular lesions, a detailed examination and diagnosis it is required, and even unlikely clinical scenarios should be considered.

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Primary leiomyosarcoma of the great saphenous vein: A case report

Cited by 6 publications

References 31 publications

Acute Jejunal Leiomyosarcoma: A Rare Case Study

Acute Jejunal Leiomyosarcoma: A Rare Case Study

Great saphenous vein leiomyosarcoma mimicking thrombosed aneurysm: A case report and review of the literature

Multifocal Sarcoma Mimicking Superficial Vein Thrombosis of the Leg: A Case Report

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