Primary Leiomyoma of the Liver: A Review of a Rare Tumour

Omiyale, Ayodeji Oluwarotimi

doi:10.1155/2014/959202

Cited by 15 publications

(15 citation statements)

References 40 publications

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“…Its occurrence in immunocompetent patients is extremely rare. Less than fifty cases are reported in literature; twenty-three of them in immunocompetent patients (4,5). This is the 24 th described.…”

Section: Introductionmentioning

confidence: 84%

Primary leiomyoma of the liver in an immunocompetent patient

Coletta

Parrino

Nicosia

et al. 2020

IRDR

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Primary leiomyoma of the liver (PLL) is a rare benign tumor occurring in immunosuppressed people. From 1926 less than fifty cases are reported in the scientific literature and about half are in immunocompetent patients. Etiology of this kind of lesion is not yet well known. We report a case of primary hepatic leiomyoma in a 60-year-old immunocompetent woman. The patient presented with lipothymia with unexpected vomiting. She underwent an ultrasound (US), and a computed tomography (CT) scan that revealed the presence of a single, solid lesion about 9 cm located between the S5 and S8 segment of the liver. It showed a well-defined, heterogeneous hypodensity with internal and peripheral enhancement and various central hypoattenuating areas and no wash-out in the portal and the late phases. Because of her symptoms and the risk of malignancy, the patient underwent a surgical liver resection. Histological diagnosis was primary leiomyoma of the liver. The patient had an uneventful recovery and was discharged after 7 days. At 30 months follow-up there were no symptoms and no evidence of disease. Leiomyoma of the liver is a rare benign neoplasm of which clinical symptoms are nonspecific and the exact radiological diagnosis still remains a challenge for radiologists. Etiology is still unclear and usually PLL represents an incidental diagnosis. Surgery plays a primary role not only in the treatment algorithm, but also in the diagnostic workout.

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Section: Introductionmentioning

confidence: 84%

Primary leiomyoma of the liver in an immunocompetent patient

Coletta

Parrino

Nicosia

et al. 2020

IRDR

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“…The mean age of presentation was 43 years (range 5-87), with a mean size of 8.7 cm (range 2-30) and a female prevalence [10][11][12]. The review of 36 cases of hepatic leiomyomas done by Omiyale [13] in 2014 showed that 55.6% of the affected patients were women, with equal distribution between the right and left lobes. Imaging methods cannot differentiate between primary hepatic leiomyoma and other differential diagnoses.…”

Section: Discussionmentioning

confidence: 99%

Hepatic Myxoid Leiomyoma: A Very Rare Tumor

Fraga

Oliveira

Terracciano

et al. 2019

GE Port J Gastroenterol

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Introduction: Mesenchymal tumors of the liver are rare, and in this group, myxoid leiomyomas are even rarer. So far, only 2 cases have been reported in the literature. Case Presentation: We aim to report the case of a 16-year-old female with a large lesion on the right hepatic lobe, grossly composed of gelatinous and heterogeneous tissue. Discussion: Histological evaluation revealed a benign mesenchymal neoplasm with expansive growth, paucicellular, with monotonous and dispersed spindle and ovoid cells, positive for α-smooth actin and h-caldesmon, without atypia or mitoses, consistent with the diagnosis of primary myxoid leiomyoma.

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“…Average length of asymptomatic period was 33 months. The authors suggested that the diagnosis of primary leiomyoma was quite rare but cure could only be achieved by definitive surgery so great attention should be paid to differential diagnosis and treatment in liver masses [ 7 ]. Harish et al published the case of a postmenopausal woman who presented with the complaints of abdominal pain and swelling in left inguinal region.…”

Section: Discussionmentioning

confidence: 99%

Round Ligament of Uterus Leiomyoma: An Unusual Cause of Dyspareunia

Birge

Arslan

et al. 2015

Case Reports in Obstetrics and Gynecology

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Round ligament of uterus leiomyoma is a rare, benign tumor of the vulva. Its incidence is not known exactly, and the mean age ranges from 13 to 70. Although clinical properties of benign and malignant diseases in the vulvar area are frequently similar, early diagnosis and treatment are essential. Local excision is recommended as definitive therapy. We present an 28-year-old female without any birth with a mass in anterior vaginal wall diagnosed as vulvar leiomyoma. In conclusion, a brief review of relevant literature emphasizes that leiomyomas are quite rare outside of the uterus but they might occur in any tissue or organ containing smooth muscle, spontaneously or parasitically after the spreading effect of an accident or surgical trauma. Clinicians should be alert especially for the diagnosis in a tissue with smooth muscle content.

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Primary Leiomyoma of the Liver: A Review of a Rare Tumour

Cited by 15 publications

References 40 publications

Primary leiomyoma of the liver in an immunocompetent patient

Primary leiomyoma of the liver in an immunocompetent patient

Hepatic Myxoid Leiomyoma: A Very Rare Tumor

Round Ligament of Uterus Leiomyoma: An Unusual Cause of Dyspareunia

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