Primary left heart malignant fibrous histiocytoma

Abstract

We present the case of a 53 years-old woman presenting with congestive heart failure and pleural and pericardial effusions, in whom transthoracic and transesophageal echocardiography revealed multilocular cardiac tumor involving the left atrium wall, extending into the pericardium. Tumor was excised surgically and proved to be a malignant fibrous histiocytoma, primarily confined to the heart. Despite surgery followed by chemotherapy, the patient died a few months later. This is the 47th case of primary cardiac fibrous malignant histiocytoma reported in the literature. The pericardial involvement has been only rarely reported. Echocardiography was the method of diagnosis before rapid referral to surgery.

Primary malignant fibrous histiocytoma involving the left pulmonary vein presenting as a left atrial tumor

“…However, majority of the reported cases showed rapid progression, in terms of recurrence, local infiltration and distant metastasis, with clinical deterioration in a short time and eventual death. [8] Complete surgical resection helps ameliorate symptoms and obtain histologic information.…”

Primary malignant fibrous histiocytoma of the heart

“…1 The first case of cardiac MFH was reported by Shah et al 2 in 1978; and 47 cases have since been reported in the literature. 3,4 According to a thorough analysis of the reported cardiac MFH cases by Okamoto et al, the patients' ages ranged from 17 to 77 years, with 62% of the patients female. The most common location of the MFH was the The patient was discharged 15 days after the operation in good condition, and UCG was repeated every 2-3 months.…”

Malignant fibrous histiocytoma originating from right ventricular outflow tract

“…Echocardiography is the primary tool for the diagnosis of cardiac tumors, but histological findings after surgery are necessary for a definite diagnosis. 4,5 The prognosis of MFH is usually poor. Survival of patients ranges from less than 1 month to 6 years, and averages approximately 1 year.…”

“…Echocardiography is the primary tool for the diagnosis of cardiac tumors, but histological findings after surgery are necessary for a definite diagnosis. 4,5…”