Primary laryngeal sarcomas in a Mexican population: Case series of eleven cases

Abstract

KEYPOINTSLaringeal sarcomas were more prevalent in men (10 cases in our series, with a mean age of 53.8 years (range: 21-81 years).Most tumours were found to be supraglottic (four cases) and glottic (four cases), one subglottic, and two extended to all subsites in the larynx.The following treatments were performed: six patients underwent organ-preserving surgery, four patients had total laryngectomy and one patient refused treatment.Only two patients received adjuvant radiotherapy, and three (27.3%) patients experienced recurrence.The heterogeneity of these types of tumours makes them difficult to study. Prognosis depends on the sarcoma subtype and grade of differentiation.

Prognostic factors for laryngeal sarcoma and nomogram development for prediction: a retrospective study based on SEER database

“…It represents only 2-3% of throat cancers, and the majority (about 93%) of patients are male (4,12,14). Studies suggested that alcohol addiction, smoking, and radiation exposure are more than likely the significant risk factors for laryngeal carcinosarcoma, and approximately 87% and 48% of these patients had a history of smoking and drinking, respectively (5,12). The most common site of primary laryngeal carcinosarcoma is the vocal cord, and so most patients experience hoarseness, and, at the advanced stage, some patients present with shortness of breath as the primary symptom.…”

“…Primary sarcoma of the larynx is rare, less than 1% of all larynx malignancies comprising less than 1% of laryngeal neoplasms in adults (1,2). Laryngeal sarcoma can arise from bone, cartilage, muscle, lipomatous, neuronal, and connective tissue, and is most commonly seen in the form of laryngeal chondrosarcoma (3)(4)(5)(6). Other sarcomas are scarce and usually reported as case reports or small series (3)(4)(5)(6)(7)(8).…”

“…Laryngeal sarcoma can arise from bone, cartilage, muscle, lipomatous, neuronal, and connective tissue, and is most commonly seen in the form of laryngeal chondrosarcoma (3)(4)(5)(6). Other sarcomas are scarce and usually reported as case reports or small series (3)(4)(5)(6)(7)(8). The diagnosis of laryngeal sarcoma mainly depends on pathology.…”

Transoral orthodromic temporalis muscle transfer technique for the paralysed midface: Our learning curve experience from the first 10 cases

“…These patients even- 9 Overall, the improvement in quality-of-life scores obtained in this case series is comparable to more advanced techniques such as gracilis muscle free flaps. 10 The data presented here have focused on patient-reported outcome measures at short-term follow-up. We have not objectively evaluated the degree of smile or lip excursion following this technique.…”