Primary intraosseous squamous cell carcinoma derived from a dentigerous cyst

Hino, Shinjiro; Tanaka, Hiroshi; Nakashiro, Koh‐ichi; Hamakawa, Hiroyuki

doi:10.1016/j.ajoms.2015.12.007

Cited by 3 publications

(1 citation statement)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Considering that it infiltrates the bone immediately from the early stages, and that clinical symptoms do not manifest easily, it is difficult to detect PIOSCC in the early stages, implying that the prognosis is generally not considered to be optimistic [3]. According to earlier reports, clinical symptoms include pain in the affected area, along with swelling and other indications of infection; however, in some cases, there are no obvious symptoms [4, 5]. In the early stages, the oral mucosa is normal, and in several cases, the first symptoms to appear include pain and slight looseness of the tooth, which tend to result in a diagnosis of periodontitis.…”

Section: Discussionmentioning

confidence: 99%

Primary Intraosseous Squamous Cell Carcinoma Arising from a Dentigerous Cyst of the Maxillary Wisdom Tooth

et al. 2020

View full text Add to dashboard Cite

The World Health Organization defines primary intraosseous squamous cell carcinoma (PIOSCC) as a squamous cell carcinoma (SCC) arising primarily within the jaws and having no connection with the oral mucosa. Here, we report a case of PIOSCC in which it was difficult to differentiate the condition from pericoronitis of an impacted maxillary wisdom tooth. The patient was a 27-year-old pregnant woman with a pain in the right maxillary wisdom tooth. The pain was diagnosed as pericoronitis of the right maxillary wisdom tooth, and the tooth was extracted under local anesthesia. During extraction, soft tissue was observed in the coronal part of the tooth, and it was diagnosed as SCC arising in a dentigerous cyst. Because the tumor may still be present, surgical resection was performed under general anesthesia. There has been no recurrence or metastasis at the 1-year follow-up. This case was histopathologically considered from being a benign odontogenic tumor to a malignant tumor. However, it revealed an extensive aberrant type and invasion equivalent to SCC. Thus, the histopathological diagnosis was PIOSCC arising from a dentigerous cyst. Although advanced cases of PIOSCC have been published, diagnosis of PIOSCC in the early stages is rare. In this case, we diagnosed pericoronitis of an impacted maxillary wisdom tooth and extracted the tooth. Therefore, we discovered it accidentally. In the early stages, diagnosis can be difficult both clinically and histopathologically.

show abstract

Section: Discussionmentioning

confidence: 99%

Primary Intraosseous Squamous Cell Carcinoma Arising from a Dentigerous Cyst of the Maxillary Wisdom Tooth

et al. 2020

View full text Add to dashboard Cite

show abstract

A Case of Primary Intraosseous Squamous Cell Carcinoma Arising in Dentigerous Cyst of Mandible

Yamagata

Fukuzawa

Inoue

et al. 2022

J. Maxillofac. Oral Surg.

View full text Add to dashboard Cite

Transformation of Odontogenic Cysts to Neoplasms - A Systematic Review

Sulistyani,

Iskandar,

Zairinal

et al. 2023

Annals of Maxillofacial Surgery

View full text Add to dashboard Cite

Background: Odontogenic cysts have the potential to transform into neoplasms. However, the characteristics of those which transformed to neoplastic tissues have not been well described and the exact causes of that phenomenon are not yet clear. Objectives: This study aims to describe characteristics of odontogenic cysts that transformed into neoplasms and to look for their potential etiologies. Data Sources: English-written studies indexed in PubMed, Science Direct, and Proquest were assessed using keywords verified by Medical Subject Headings: ‘Odontogenic Cyst’ and ‘Neoplastic Cell Transformation’. Study Eligibility Criteria: Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines were used as guidance. Participants: Following steps in PRISMA guidelines, 19 articles were fully reviewed (three case series and 16 case reports) with 27 subjects of 16 males (59%) and 11 females (41%) from 15 to 86 years old. Results: Cystic origins were eight dentigerous cysts, four odontogenic keratocysts, two residual cysts, one radicular cyst, one calcifying odontogenic cyst, one follicular cyst, one glandular odontogenic cyst, and nine unspecified odontogenic cysts that transformed to ameloblastoma (3 cases) and carcinoma (24 cases). Limitations: Neoplastic transformations of odontogenic cysts arose from epithelial remnants of inadequate odontogenic cyst removal and chronic inflammation due to infection. However, the exact causes of their transformations remain unclear. Conclusions: Therefore, careful removal of odontogenic cysts and regular postoperative follow-ups are key to prevent recurrence and neoplastic transformation. Future studies are needed to investigate potential causes of neoplastic transformation of odontogenic cysts.

show abstract

Primary intraosseous squamous cell carcinoma derived from a dentigerous cyst

Cited by 3 publications

References 12 publications

Primary Intraosseous Squamous Cell Carcinoma Arising from a Dentigerous Cyst of the Maxillary Wisdom Tooth

Primary Intraosseous Squamous Cell Carcinoma Arising from a Dentigerous Cyst of the Maxillary Wisdom Tooth

A Case of Primary Intraosseous Squamous Cell Carcinoma Arising in Dentigerous Cyst of Mandible

Transformation of Odontogenic Cysts to Neoplasms - A Systematic Review

Contact Info

Product

Resources

About