Primary intraosseous meningioma of orbit and anterior cranial fossa: A case report and literature review

Abstract

Primary intraosseous meningiomas of the skull base are rare. Extensive involvement of the skull base by the tumour may result rarely in loss of vision. Surgical management requires extensive decompression and reconstruction. A case of primary intraosseous meningioma of orbits and anterior cranial fossa presenting with painless proptosis and loss of vision is presented here and the literature reviewed.

Effect of Etidronate on Intraosseous Meningioma

“…On rare occasions, meningiomas also occur in extradural lesions including calvarium, paranasal sinuses, parotid glands, neck and skin [1,2]. In these cases ectopic meningiomas seem likely to arise outside of meninges from nests of arachnoid cells along the lines of fusion of the embryonic skull or otherwise from multipotential mesenchymal cells [2].…”

“…1D). Among 39 reported cases of intraosseous meningioima, the most common site of involvement is the orbit followed by the fronto-parietal region and anterior cranial fossa [1][2][3]. Hyperosteosis is the most common radiographic abnormality, and is found in 60% of the cases.…”

Intradiploic Orbital Roof Meningioma with Pneumosinus Dilatans in a Child: A Case Report and Review of the Literature

“…Meningiomas as primary tumors may arise in the calvaria, scalp, orbit, paranasal sinuses, nasopharynx, neck and skin [1,2,3,4,5,6,7,8,9]. Meningiomas that arise in locations outside the dural compartment are termed ectopic, epidural, calvarial, intraosseous or PEMs [1,2,3,4].…”

“…• arachnoidal cell presence in the sheaths of nerves and vessels exiting various skull foramina [1,2,6,7,9], and…”

Completely Intraosseous Atretic Meningocele

“…The pathological potential of intradiploic rests of arachnoid cells has been well documented in cases presenting as primary intraosseous meningiomas [15,16,17,18,19]. The pathogenesis of primary intraosseous meningiomas is from ectopically located intradiploic arachnoid cell rests, which may result from entrapment during embryonal development, following trauma with a skull fracture and dural laceration, entrapment in a cranial suture during birth, or from multipotential mesenchymal cells [15, 20, 21].…”