“…Medical management, percutaneous ultrasound‐guided ethanol ablation and surgical excision have been described for treatment of PHPT, with surgical excision being the treatment choice with the highest success rate of 90%–95% across species in cases of complete removal of all autonomously functioning tissue (Karstrup et al, 1990; Rasor et al, 2007; Walker & Silverberg, 1992). There are many factors which contribute to surgical failure including the presence of multi‐gland disease and misidentification of abnormal tissue on ultrasonography, scintigraphy, or intraoperatively.…”
Primary hyperparathyroidism is a well-characterised endocrinopathy in which chief cells within the parathyroid gland produce and secrete an excessive amount of parathyroid hormone (PTH), ignoring physiological negative feedback mechanisms. This results in clinically significant electrolyte derangements, specifically hypercalcaemia and hypophosphataemia, which can lead to anorexia, weight loss, osteodystrophia fibrosa of the facial bones, osteopenia and lame-
“…Medical management, percutaneous ultrasound‐guided ethanol ablation and surgical excision have been described for treatment of PHPT, with surgical excision being the treatment choice with the highest success rate of 90%–95% across species in cases of complete removal of all autonomously functioning tissue (Karstrup et al, 1990; Rasor et al, 2007; Walker & Silverberg, 1992). There are many factors which contribute to surgical failure including the presence of multi‐gland disease and misidentification of abnormal tissue on ultrasonography, scintigraphy, or intraoperatively.…”
Primary hyperparathyroidism is a well-characterised endocrinopathy in which chief cells within the parathyroid gland produce and secrete an excessive amount of parathyroid hormone (PTH), ignoring physiological negative feedback mechanisms. This results in clinically significant electrolyte derangements, specifically hypercalcaemia and hypophosphataemia, which can lead to anorexia, weight loss, osteodystrophia fibrosa of the facial bones, osteopenia and lame-
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