Primary hepatic myelolipoma: A case report and review of the literature

Li, Keyu; Wei, Ailin; Li, Ang

doi:10.12998/wjcc.v8.i19.4615

Cited by 4 publications

(2 citation statements)

References 27 publications

(13 reference statements)

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“…Myelolipoma is usually asymptomatic in the case of a small lesion, but spontaneous rupture due to mass effect, acute abdomen, and bleeding may occur as the lesion grows[ 1 ]. Resection is unnecessary unless the diagnosis is unclear or the lesion is symptomatic[ 6 ].…”

Section: Discussionmentioning

confidence: 99%

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Indium chloride bone marrow scintigraphy for hepatic myelolipoma: A case report

Sato¹,

Saito²,

Abe³

et al. 2023

World J Clin Cases

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BACKGROUND As hepatic myelolipoma is rarely encountered, its radiological diagnosis using ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI) is challenging. Hepatic myelolipoma is similar to fat-contained hepatic lesions seen in hepatocellular carcinoma and angiomyolipoma. Therefore, further development of techniques to diagnose hepatic myelolipoma is warranted. CASE SUMMARY A 44-year-old obese man was found to have a hepatic lesion during his medical checkup. The lesion was 50 mm × 57 mm in size and was detected in segment 8 (S8) of the liver by US. The patient was diagnosed with hepatic lesion 20 years ago, but it was left unresolved. The patient had no symptoms, liver dysfunction, hepatitis virus antibody, or tumor marker elevation. Plain CT showed a well-defined lesion in S8 of the liver. The central and peripheral areas of the lesion primarily exhibited fat density and hypodensity, respectively. MRI revealed a capsule-like structure. Biopsy was performed to address the probability of hepatocellular carcinoma. The lesion was pathologically confirmed as a myelolipoma. Bone marrow scintigraphy performed using 111 InCl 3 revealed accumulation of the radiopharmaceutical in the soft tissue component, except in the fat-dominant part of the tumor, as well as in the surrounding liver parenchyma due to the presence of reticuloendothelial cells in the liver. CONCLUSION This is the first report on the diagnosis of hepatic myelolipoma using 111 InCl 3 scintigraphy. The effectiveness of bone marrow scintigraphy for diagnosing hepatic myelolipoma might be limited. As radiopharmaceuticals accumulate in both hematopoietic and reticuloendothelial cells, the accumulation of radiopharmaceuticals in the lesion is obscure.

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Section: Discussionmentioning

confidence: 99%

“…Therefore, the efficacy of the radiopharmaceutical was confirmed. However, the conspicuity of the accumulation of radiopharmaceutical was weak because it accumulated in the surrounding liver parenchyma owing to the presence of reticuloendothelial cells[ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Indium chloride bone marrow scintigraphy for hepatic myelolipoma: A case report

Sato¹,

Saito²,

Abe³

et al. 2023

World J Clin Cases

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Unique case of metachronous adrenal and hepatic myelolipomas

2021

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We present a unique case of metachronous adrenal and hepatic myelolipomas in a 62-year-old man. Myelolipomas are most commonly found in the adrenal gland, with extra-adrenal sites such as the lung, retroperitoneum and liver reported. They are a form of benign mesenchymal tumour, with only 25 case reports of a hepatic location published to date. The are no guidelines to its management. Our patient underwent resection due to pain, and after a complicated postoperative period is pain free.

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Bronchoscopic treatment of multiple bronchial myelolipomas: a case report and literature review

Ji,

Zhong,

Ren

et al. 2023

BMC Pulm Med

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Background Extra-adrenal myelolipoma is an unusual entity, and endobronchial myelolipoma is rarer, which is often ignored by clinicians, delaying the disease and affecting the prognosis. Case presentation A 71-year-old man with a history of chronic obstructive pulmonary disease (COPD) and type 2 diabetes mellitus, with recurrent fever, cough, and expectoration for more than 2 weeks experienced relief in cough, phlegm reduction, and glycemic control with anti-inflammatory treatment. Further examination revealed that new growths obstructing all lobar bronchi impaired flexible bronchoscope entry. In order to relieve the patient’s symptoms, under general anesthesia, we performed liquid nitrogen cryobiopsy at multiple bronchial openings, and then used argon plasma coagulation (APC) to achieve hemostasis. The pathological diagnosis was bronchial myelolipoma. The largest volume of the resected tissue was a mass measuring 0.6 cm × 0.4 cm × 0.3 cm at the bronchial opening of the upper lobe of the left lung. The patient’s condition was stable and the symptoms were partially relieved after surgery. No recurrence was observed during the 12-month follow-up, although the long-term treatment efficacy is unknown. Conclusion Pathological biopsy is key to the diagnosis of endobronchial myelolipoma, and the development of the endobronchial myelolipomas may have been associated with long-term poor control of steroid levels in this patient.

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Primary hepatic myelolipoma: A case report and review of the literature

Cited by 4 publications

References 27 publications

Indium chloride bone marrow scintigraphy for hepatic myelolipoma: A case report

Indium chloride bone marrow scintigraphy for hepatic myelolipoma: A case report

Unique case of metachronous adrenal and hepatic myelolipomas

Bronchoscopic treatment of multiple bronchial myelolipomas: a case report and literature review

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