Primary gonadotropin releasing hormone and adjunctive human chorionic gonadotropin treatment in cryptorchidism: A clinical trial

Nane, İ.; Ziylan, Orhan; Esen, Tarık; Koçak, Taner; Ander, Haluk; Tellaloĝlu, S.

doi:10.1016/s0090-4295(96)00359-7

“…hCG therapy with or without combination of nasal spray of GnRH has been shown to be effective to treat cryptorchidism in neonates and prepubertal boys (304,305). This finding could represent a further benefit of neonatal treatment of children with CHH, as cryptorchidism is a factor of poor prognosis for adult fertility and is also a risk factor for testicular malignancy.…”

Section: Advance Article: Endocrine Reviewsmentioning

confidence: 89%

Clinical Management of Congenital Hypogonadotropic Hypogonadism

Young

¹

,

Xu

²

,

Papadakis

³

et al. 2019

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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“…Hormonal treatment of cryptorchidism has been used to stimulate the secretion of testicular androgens and to override the imbalance leading to testicular retention [3, 11]. hCG and GnRH, alone or combined in various treatment schedules, are the main used hormones [2, 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15], but their efficacy remains a debated issue [1, 2, 4]. In fact, great variation in testicular descent has been reported [2, 4], ranging from 0 to 90% [2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 13, 14, 15].…”

Section: Discussionmentioning

confidence: 99%

“…hCG and GnRH, alone or combined in various treatment schedules, are the main used hormones [2, 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15], but their efficacy remains a debated issue [1, 2, 4]. In fact, great variation in testicular descent has been reported [2, 4], ranging from 0 to 90% [2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 13, 14, 15]. The inclusion of heterogeneous patient populations regarding the type of cryptorchidism (unilateral or bilateral), the site of testicular retention (abdominal or impalpable, inguinal, suprascrotal, high scrotal), and the age at hormonal treatment (from 1st year of life to adolescence) are considered causes of the different clinical results [1, 2, 3, 4, 13].…”

Section: Discussionmentioning

confidence: 99%

Hormonal Treatment for Unilateral Inguinal Testis: Comparison of Four Different Treatments

Bertelloni¹,

Baroncelli²,

Ghirri³

et al. 2001

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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“…Patients with unilateral testicular absence should also be offered ment of UDT with both hCG and GnRH with encouraging results. 34 Studies support the use of GnRH in promoting the development of germ cells, as well as in promoting testicular descent. The results are variable, but the side effects are less than those seen with hCG.…”

Section: A N a G E M E N Tmentioning

confidence: 98%

The undescended testicle

Wolf

¹

,

Maizels

²

,

FURNESS

³

2001

Get access via publisher Add to dashboard Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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Primary gonadotropin releasing hormone and adjunctive human chorionic gonadotropin treatment in cryptorchidism: A clinical trial

Cited by 11 publications

References 23 publications

Clinical Management of Congenital Hypogonadotropic Hypogonadism

Clinical Management of Congenital Hypogonadotropic Hypogonadism

Hormonal Treatment for Unilateral Inguinal Testis: Comparison of Four Different Treatments

The undescended testicle

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