Primary extranodal non-Hodgkin's lymphomas. Part 2: Head and neck, central nervous system and other less common sites

Primary Extra Nodal Non Hodgkin Lymphoma: A 5 Year Retrospective Analysis

“…Primary central nervous system lymphoma (PCNL) is defined as lymphoma arising in and confined to the cranial-spinal axis (brain, eye, leptomeninges and spinal cord). Formerly a rare tumour, PCNL has shown increased incidence both in immunocompromised (congenital, acquired or iatrogenic) high-risk groups and in the general population (Zucca et al, 1999). Various multi institutional studies from India in recent past, have addressed the changing trends of PCNL in regard to incidence, risk factors, and pathophysiology (Sarkar et al, 2005;Paul et al, 2008;Mahhdoomi et al, 2011).…”

“…These forms are referred to as primary extranodal lymphomas (pENL). At least one-fourth of the lymphomas are probably of extranodal origin (Isaacson, 1994;Zucca et al, 1997;Zucca et al, 1999;Ferry, 2008).…”

A Systematic Overview of Radiation Therapy Effects in Non-Hodgkin's Lymphoma

“…The tonsils are the most common site followed by nasopharynx, oral cavity, salivary glands, paranasal sinuses and the base of the tongue. The therapy results vary greatly depending on histology and anatomical site (71).…”

Extranodal and splenic small B-cell lymphoma

“…[1][2][3] Involvement of extranodal sites and the spleen by lymphoma is not an uncommon occurrence. A proportion of these cases will be secondary involvement by disseminated nodal lymphoma and all nodal small B-cell lymphomas have the potential to involve extranodal sites or the spleen.…”