Primary Ewing's sarcoma of zygoma

Abstract

Ewing's sarcoma is a small round cell tumor, malignant in nature, typically affecting long bones and pelvis. It is most commonly presented in the pediatric age group. The occurrence of Ewing's sarcoma in the head-and-neck region is rare and is reported to be around 2%–3%, of which chances of having primary lesion are rarer. Among facial bones, mandible is the most commonly affected bone. Primary involvement of zygoma is extremely rare. Here, we present a case of primary Ewing's sarcoma of the left zygoma in a 17-year-old girl. The diagnosis was made after surgical resection, histopathology with immunohistochemistry confirmation, and cytogenetic study.

Ewing’s Sarcoma of the Zygoma: A Very Rare Location

“…In our review, two patients underwent surgery followed by adjuvant chemotherapy, three underwent neoadjuvant chemotherapy followed by surgery, one underwent surgery followed by radiotherapy and chemotherapy, one underwent chemotherapy and radiotherapy, and one underwent surgery only [1][2][3][4][5][6][7][8][9]. We report a case in which the patient received neoadjuvant chemotherapy, and the tumor progressed during treatment, which could suggest some chemotherapy resistance.…”

“…Ewing´s sarcoma is more prevalent among young people. Most cases occur between the ages of five and 25 years [ 9 ]. Patients' ages ranged from two to 31 years in our review.…”

“…Some authors have argued that maxillofacial lesions have a better prognosis than lesions in other locations. This is because local signs, such as swelling, are more visible [ 2 , 3 , 9 ]. Although the treatment is well-defined in other locations, the best treatment sequence for maxillofacial tumors remains controversial.…”