Primary Diphtheritic Otitis Media: Review of the Literature and Report of a Case

Downes, John J.

doi:10.1001/archotol.1959.00730040031005

Cited by 5 publications

(2 citation statements)

References 19 publications

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“…However, this is found in only 23% of reported cases as per the review by Downes et al (1959) [18]. Hence bacteriological confirmation is important.…”

Section: Discussionmentioning

confidence: 98%

“…The three varieties of diphtheritic otitis media that have been reported are, i) primary diphtheritic otitis media, where middle ear is the main site of infection with isolation of organisms from ear discharge and not from the nasopharynx; ii) secondary diphtheritic otitis media where ear is involved as a complication of preexisting nasopharyngeal diphtheria and obvious positive cultures obtained from the ear and nasopharynx; and iii) superimposed infection by C. diphtheriae upon an existing otitis media due to the usual respiratory pathogens like streptococci, pneumococci or Haemophilus infleuenzae [16]. Primary diphtheritic otitis media is rare and has been reported in few old studies [16][17][18][19]. In the case presented here, the organism was isolated in addition to organisms like Pseudomonas aeruginosa and Klebsiella pneumoniae which are the potential pathogens associated with CSOM.…”

Section: Discussionmentioning

confidence: 99%

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Isolation of Toxigenic Corynebacterium diphtheriae from Chronic Suppurative Otitis Media

Gaikwad¹,

Arora²,

Gade³

et al. 2017

JCR

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Background: A major shift in the pathogenic potential of Corynebacterium diphtheriae is being witnessed globally, consequent to the successful diphtheria immunization. However, its isolation from unconventional sites like middle ear has been rarely implicated in the available literature. Case Report: Here we describe a case of chronic suppurative otitis media (CSOM) in a fully immunized young adult patient from whom, Pseudomonas aeruginosa and Klebsiella pneumoniae were isolated as the major pathogens with simultaneous isolation of toxigenic Corynebacterium diphtheriae. The patient had no evidence of Corynebacterium diphtheriae infection on clinical examination, until the organism was incidentally isolated on culture suggesting the possibility of colonization or superimposed infection. Conclusion: Although, the condition was successfully managed with surgical and medical intervention with good outcome, this incidence warrants clinician's attention towards unusual occurrence of a potentially dangerous pathogen. Considering the likelihood of its passive environmental shedding which may pose unseen threat of emergence of fatal diphtheria in the contacts and other susceptible local population, active screening for its carriage is advisable.

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“…However, this is found in only 23% of reported cases as per the review by Downes et al (1959) [18]. Hence bacteriological confirmation is important.…”

Section: Discussionmentioning

confidence: 98%