Primary diffuse large B‐cell lymphoma presenting as acute appendicitis: A report of 2 cases and a literature review

Abstract

Primary appendiceal lymphomas (PAL) are a type of primary gastrointestinal non‐Hodgkin lymphoma (PGINHL) with an incidence of <1%. There is considerable discordance with regard to the optimal management of PGINHL. We describe two cases of PAL, perform a literature review, and discuss the available evidence for optimal treatment.

Hidden lymphoma in the appendix: a case of primary appendiceal diffuse large B-cell lymphoma presenting as acute appendicitis

“…Available treatment options are limited. However, recent studies have shown that combining surgical resection and postoperative chemotherapy can offer promising outcomes for patients with localized intestinal DLBCL [ 7 ]. The surgical resection involves the removal of the affected appendix, followed by the administration of CHOP chemotherapy, which is highly effective in eradicating cancer cells.…”