Primary Cutaneous Rosai-Dorfman Disease of the Scalp

Mizuta, Haruki; Nakano, Eiji; Yamazaki, Naoya

doi:10.5826/dpc.1101a86

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“…Rosai-Dorfman-Destombes disease (RDD) is a non-neoplastic, benign, idiopathic non-Langerhans cell histiocytosis presenting in children and young adults. It mostly affects cervical lymph nodes, but approximately 40% of cases have extranodal lesions ( 1 ). Destombes first reported this disease in 1965 ( 2 ), then Juan Rosai and Ronald Dorfman described this disorder 4 years later ( 3 , 4 ).…”

Section: Introductionmentioning

confidence: 99%

A primary Rosai-Dorfman-Destombes disease of the scalp: case report and literature review

et al. 2023

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BackgroundRosai-Dorfman-Destombes disease (RDD) was first described in 1965 as a benign histiocytic proliferative disorder of unknown cause. Cases of RDD limited to cutaneous tissue have been reported over the past few decades, but single cutaneous RDD of the scalp is rare.Case presentationWe report a 31-year-old male with a lump on the parietal scalp without extranodal lesion lasting 1 month with gradual enlargement. The surgical incision ruptured with purulent after the first resection. Then the patient was treated with plastic surgery after disinfection and antibiotic treatment. Finally, he recovered well and discharged after 20 days.ConclusionsRDD of the scalp is rare. Surgical incision can cure the lesion but it may become infected because of increased lymphocytic infiltration. Early diagnosis and differential diagnosis of RDD are necessary. For treatment, individualized therapy is critical to patient prognosis.

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Section: Introductionmentioning

confidence: 99%