Primary cutaneous rhabdomyosarcoma: Case report and review of published work

Kim, Yoon Seob; Lee, Ji Hyun; Lee, Jun Young; Park, Young Min

doi:10.1111/1346-8138.13011

Cited by 4 publications

(6 citation statements)

References 5 publications

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“…2 It rarely occurs on the skin and superficial dermis, as primary sites. 3 Rhabdomyosarcoma in the head and neck region can be divided into three subgroups: orbital, parameningeal and nonorbital nonparameningeal. 2 Almost all nonorbital nonparameningeal rhabdomyosarcomas are reported to occur in deeper tissue.…”

Section: Discussionmentioning

confidence: 99%

“…Rhabdomyosarcoma in the nose usually appears in the nasal cavity and rarely occurs on the skin as the primary site (comprising less than 1% of all rhabdomyosarcoma). 3 Based on histologic features, alveolar rhabdomyosarcoma and embryonal rhabdomyosarcoma are common subtypes.…”

Section: Discussionmentioning

confidence: 99%

“…Usually, alveolar rhabdomyosarcoma shows more aggressive clinical behavior with a worse prognosis than embryonal rhabdomyosarcomas. 3 Till now, very few cases of superficial primary cutaneous alveolar rhabdomyosarcoma have been reported on the nasal skin. 4 Histopathologically, the present case exhibited nests and sheets of small round tumor cells in the superficial dermis.…”

Section: Discussionmentioning

confidence: 99%

“…Focal alveoli-like structures were observed, which is an important histological feature of primary cutaneous rhabdomyosarcoma. 3 These morphological features mimic melanocytic as well as epithelial tumors. The tumor cells were strongly positive for vimentin, myoblast determination protein 1, desmin, myogenin and negative for S-100, smooth muscle actin, leukocyte common antigen and CD3.…”

Section: Discussionmentioning

confidence: 99%

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A red nodule on the tip of the nose in a Chinese girl

Fu¹,

Zhang³

et al. 2021

IJDVL

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A red nodule on the tip of the nose in a Chinese girlA 7-year-old girl presented with a red nodule on the apex of the nose for 1 month without any other symptom. Skin examination revealed a well-defined, round, pink nodule measuring 1.2 × 1.5 cm with a hard texture [Figure 1a]. Her past medical history was unremarkable.An incisional biopsy showed normal epidermis and nests or sheets of small round cells with atypical nuclei and scanty cytoplasm in the reticular dermis. The tumor cells formed alveolar structures. Necrosis, cross striations or obvious mitotic activity were absent [Figures 1b and c]. Immunohistochemical studies demonstrated that the tumor cells were strongly positive for vimentin, myoblast determination protein 1, desmin and myogenin, weakly positive for myoglobin (focal), synaptophysin, cytokeratin and Ki-67 (30% +); and negative for S-100, smooth muscle actin and cluster of differentiation (CD) 3 [Figures 2a-d].

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A red nodule on the tip of the nose in a Chinese girl

Fu¹,

Zhang³

et al. 2021

IJDVL

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“…While conventional RMS has a slight male predominance, PC-RMS tends to be more common in females [11]. Among pediatrics, the face tends to be the most frequently affected site with PC-RMS [1,2,9,[12][13][14][15]. Other rarely involved sites include the hand [16], chest [17], feet [12], anus [18,19], and the perineum [20].…”

Section: Rhabdomyosarcomamentioning

confidence: 99%

Congenital Primary Cutaneous Rhabdomyosarcoma of the Perineum with Mixed Histopathological Features and Unusual Expression of Smooth Muscle Actin: Report of a Case

Mre¹

2017

CDOAJ

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Rhabdomyosarcoma (RMS) affecting the soft tissue of the perianal and perineal regions in children is uncommon and account for 2% of all rhabdomyosarcomas. Primary cutaneous presentation in this anatomical location is extremely rare.We report a 9-month-old female infant with a congenital primary cutaneous RMS presenting as a polypoidal exophytic mass in the perineum mimicking giant condyloma acuminatum (Buschke and Löwenstein tumor). Histopathological examination revealed a predominantly alveolar RMS with areas showing embryonal and pleomorphic features. In addition to expressing desmin and myogenin, the tumor cells also expressed smooth muscle actin.

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Primary alveolar rhabdomyosarcoma of the breast skin: a case report and literature review

Surkova

Волченко

Nikitina

et al. 2022

Opuholi ženskoj reproduktivnoj sistemy

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Alveolar rhabdomyosarcoma is one of the four subtypes of rhabdomyosarcoma identified by the World Health Organization. This type of malignant neoplasms more often affects deep soft tissues of extremities and occurs in young ages, regardless of gender. According to the medical literature, no more than 45 cases of the development of primary cutaneous rhabdomyosarcoma have been reported in the world. In this report, we describe a clinical case of a 40-year-old woman with primary localization of alveolar radbomyosarcoma in the skin of the mammary gland.

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Primary cutaneous rhabdomyosarcoma: Case report and review of published work

Cited by 4 publications

References 5 publications

A red nodule on the tip of the nose in a Chinese girl

A red nodule on the tip of the nose in a Chinese girl

Congenital Primary Cutaneous Rhabdomyosarcoma of the Perineum with Mixed Histopathological Features and Unusual Expression of Smooth Muscle Actin: Report of a Case

Primary alveolar rhabdomyosarcoma of the breast skin: a case report and literature review

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