Primary cutaneous infection by Aspergillus ustus in a 62-year-old liver transplant recipient

Stiller, Matthew J.; Teperman, Lewis; Rosenthal, Stanley A.; Riordan, Anne T.; Potter, J P; Shupack, Jerome L.; Gordon, Morris

doi:10.1016/s0190-9622(94)70169-5

Cited by 59 publications

(48 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To date, only 22 cases of invasive aspergillosis have been reported to be caused by A. ustus (1,13,20,21,36,37,39; also O. V. Vasilenko, N. V. Bezmelnitsyn, S. A. Keselman, E. M. Shulutko, and A. V. Pivnik, unpublished data). Almost half of these cases were classified as primarily cutaneous aspergillosis, so the skin was suggested as the primary site of infection (17,30). Invasive aspergillosis caused by A. ustus is associated with high mortality rates, primarily due to the reduced susceptibilities of A. ustus isolates to various antifungal drugs (32).…”

mentioning

confidence: 99%

Aspergillus calidoustus sp. nov., Causative Agent of Human Infections Previously Assigned to Aspergillus ustus

et al. 2008

View full text Add to dashboard Cite

Aspergillus ustus is a relatively rare human pathogen causing invasive infections in immunocompromised hosts. In this study isolates originating from clinical and other sources have been examined using molecular, morphological, and physiological approaches to clarify their species assignment. Phylogenetic analysis of partial ␤-tubulin, calmodulin, actin, and intergenic transcribed spacer sequences indicated that none of the clinical isolates recognized previously as A. ustus belongs to this species. All but two of these isolates formed a well-defined clade related to A. pseudodeflectus based on sequence analysis of protein-coding regions. Morphological and physiological examination of these isolates indicated that they are able to grow above 37°C, in contrast with A. ustus isolates, and give a positive Ehrlich reaction, in contrast with related species including A. granulosus, A. ustus, and A. pseudodeflectus. These isolates are proposed as a new species, A. calidoustus. Antifungal susceptibility testing showed that this species has decreased susceptibilities to several antifungal drugs. The triazoles are inactive in vitro, including the new azole posaconazole.

show abstract

mentioning

confidence: 99%

Aspergillus calidoustus sp. nov., Causative Agent of Human Infections Previously Assigned to Aspergillus ustus

et al. 2008

View full text Add to dashboard Cite

show abstract

“…Infections caused by Aspergillus species have increased dramatically in recent years, and, after Candida albicans, they are the most common cause of human opportunistic fungal infection in immunocompromised patients (7,9). Aspergillus fumigatus is the species which most frequently causes invasive pulmonary aspergillosis, but more than 30 other species of the genus are associated with different human and animal infections (1).…”

mentioning

confidence: 99%

Cutaneous Infection Caused by Aspergillus ustus , an Emerging Opportunistic Fungus in Immunosuppressed Patients

et al. 2001

View full text Add to dashboard Cite

We report a case of primary cutaneous infection by the emerging fungus Aspergillus ustus in an immunosuppressed patient after a domestic accident. The patient failed to respond to itraconazole and died before receiving a new treatment with amphotericin B. There have been eight other cases reported since 1973, and only two patients survived the infection. In vitro susceptibility testing of seven antifungal drugs showed that terbinafine and the new azole derivative UR-9825 were the most active against this fungus.

show abstract

“…Notably, the organism can also cause severe surgical site infections [3][4][5]. As filamentous fungi are airborne pathogens, in most cases pulmonary infection represents the initial manifestation, with subsequent spread to other organs if the infection cannot be controlled at an early stage [6].…”

Section: Introductionmentioning

confidence: 99%

Successful Management of Aspergillus Liver Abscess in a Patient with Necrotizing Fasciitis

et al. 2007

View full text Add to dashboard Cite

show abstract

Primary cutaneous infection by Aspergillus ustus in a 62-year-old liver transplant recipient

Cited by 59 publications

References 26 publications

Aspergillus calidoustus sp. nov., Causative Agent of Human Infections Previously Assigned to Aspergillus ustus

Aspergillus calidoustus sp. nov., Causative Agent of Human Infections Previously Assigned to Aspergillus ustus

Cutaneous Infection Caused by Aspergillus ustus , an Emerging Opportunistic Fungus in Immunosuppressed Patients

Successful Management of Aspergillus Liver Abscess in a Patient with Necrotizing Fasciitis

Contact Info

Product

Resources

About