Primary cutaneous follicle center lymphoma, diffuse type, with atypical clinical features

Abstract

249 not described. In our case, no rapid changes in size and color were observed in the remaining lesion on the glans over five subsequent years and, histologically, no malignant signs were found in the excised lesion. Therefore, we did not excise the lesion on the glans. Zembowicz et al. reported that sentinel lymph node metastasis may be found in up to 46% of cases of pigmented epithelioid melanocytoma, but favorable outcomes after 5year follow-up were described [8,10]. The lesion on our patient's glans is a pigmented epithelioid melanocytoma, namely, a borderline melanocytic tumor. Thus follow-up of this lesion without total excision is unprecedented and challenging, and considerable vigilance is required. Changes in dermoscopic findings should allow early detection of malignant change. We believe that the lesion was present at birth, according to embryogenetic hypothesis on divided nevus [2], but only became pigmented at the age of 8. In conclusion, pigmented epithelioid melanocytoma is a borderline melanocytic tumor with a low risk of local recurrence. Some cases without Carney complex have been reported [8], but the lesion is very rare in genital regions. Our unusual case involved a divided nevus on the penis. Diligent follow-up is necessary, not only of the lesion on the glans, but also the prepuce from which the tumor was removed.