Primary Cutaneous Follicle Center Lymphoma Presenting as a Solitary Nodule on the Forearm of an Adolescent Girl: A Case Report and Literature Review

Abstract

Primary cutaneous B-cell lymphomas (PCBCLs) are very rare to be seen in pediatric and adolescent age group, especially primary cutaneous follicle center lymphoma (PCFCL) which is considered the least occurring main subtype. Here, we describe a 16year-old girl who developed a slowly growing solitary firm smooth surfaced erythematous nodule over her forearm. Histopathological examination showed a dense dermal nodular, periadnexal and perivascular lymphoid infiltrate extending deep to the subcutis. Immunohistochemical staining showed a B-cell population with positivity for CD20, variable staining for BCL6 and CD10 and uniquely staining for BCL2. Although a primary cutaneous marginal zone lymphoma (PCMZL) was considered but the presences of interfollicular BCL6 and CD10 positivity established the diagnosis of PCFCL. To our knowledge, only 12 cases of pediatric and adolescent PCFCL have been described in the literature.

Shared psychotic disorder

“…There are certain characteristics that are often associated with each individual in the shared psychotic disorder relationship; 7,8 the primary (in this case the wife) is traditionally the more dominant individual, and the secondary (the husband) more dependent 9 . We noted that the husband was a quiet, passive man compared with his wife who appeared to be the more dominant of the two.…”

Importance of Capgras syndrome in shared psychotic disorder: a case report

“…In the next edition (DSM-IV), the term changed to shared psychotic disorder. 2 In the latest edition, DSM-V, it was removed as a separate entity and listed under the “Other specified schizophrenia spectrum and other psychotic disorders” category as “delusional symptoms in the partner of an individual with delusional disorder”. The DSM-V states that “in the context of a relationship, the delusional material from the dominant partner provides content for delusional belief by the individual who may not otherwise entirely meet criteria for delusional disorder”.…”

“…The incidence of shared psychotic disorder is difficult to estimate, but some studies report that it is responsible for approximately 2% of psychiatric hospitalizations. 2 However, this figure may be underestimated as the disorder is often missed in clinical practice because psychiatrists may treat the inducer or induced while being unaware of the existence of the delusion in the other patient(s). 1 …”

“…Earlier expert opinion that the delusions disappear in the induced person after separation from the inducer proved to be incorrect. 2 Therefore, in addition to separation, the use of antipsychotic therapy is necessary for both patients. 2 …”

“… 2 Therefore, in addition to separation, the use of antipsychotic therapy is necessary for both patients. 2 …”