Primary Cutaneous Diffuse Large B-Cell Lymphoma (Leg Type) Presenting as Necrotising Fasciitis

Abstract

Necrotising fasciitis is a rare rapidly progressive, life threatening, soft tissue infection which spreads along fascial planes. We present a patient who was diagnosed with a primary cutaneous Diffuse Large B-Cell Lymphoma (leg type) following initial presentation as probable necrotising fasciitis. Presentation was of a painful swollen leg, septic shock and MRI findings consistent with the clinical signs. Diagnosis of necrotising fasciitis remains challenging and it is often missed in the early stages. Early fascial biopsy and histopathological analysis is useful in cases where the diagnosis is unclear. We feel that this case highlights these important issues and will benefit others in their management of similar cases in the future.

Epidural abscess imitating recurrent pilonidal sinus: a case report

“…Fluid resuscitation together with electrolytes, when needed, combined with antibiotic therapy (penicillin G and aminoglycoside) is the first line approach. Surgical intervention is necessary and should be performed as soon as possible (1,4,15,17,22). Surgical debridement necrosectomy and fasciotomy together with excision of all necrotic subcutaneous tissue fascia and skin has to be performed to the point that healthy bleeding tissue is encountered.…”

“…Necrotizing fasciitis is a rapidly progressive inflammatory infection of the fascia with secondary necrosis of the subcutaneous tissue (1).…”