Primary cutaneous aspergillosis

Prasad, P. V. S.; Babu, Arjunan; Kaviarasan, P K; Anandhi, C.; Viswanathan, P. N.

doi:10.4103/0378-6323.14006

Cited by 13 publications

(7 citation statements)

References 3 publications

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“…In our case patient is a farmer by occupation and was having a history of trauma, which is comparable to study done by Singh Shergill G et al, which shows causative organism is abundant in the environment, most common sources are soil, stored grains, and decaying vegetation, so this appears to be the causative factor in our patient [12, 13,14]. Cutaneous aspergillosis is of two types: primary or secondary.…”

Section: Discussionsupporting

confidence: 86%

Cutaneous aspergillosis in an immunocompetent patient: a case report

Bagate

Birare

Jadhav

et al. 2020

Trop J Pathol Microbiol

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Cutaneous aspergillosis is a rare disease that is usually seen in immunosuppressed patients. It is rarely found in immunocompetent patients and it is mostly caused by Aspergillus. flavus, Aspergillus fumigatus, and rarely by Aspergillus niger. Cutaneous Aspergillosis is of two types: primary or secondary. Primary cutaneous aspergillosis frequently involves sites of skin injury, at or near intravenous catheter sites, at sites associated with occlusive dressings, at sites of traumatic inoculation, surgery or burns. Secondary cutaneous lesions occur as a result of either from widespread blood-borne seeding of the skin or it may occur from contiguous extension to the skin from an infected underlying structure. The current study is presenting a case of a 25-year-old female, a farmer by occupation, presented with multiple scaly plaques and verrucous nodules with a past history of trauma over knee 3 years back. After trauma she initially noticed lesions over knee followed by the elbow, face and oral lesions noticed 7 months back. There was no present or past history of weight loss, anorexia and serological tests were negative for HIV. One year back she was diagnosed as lupus vulgaris and received Anti-Tubercular treatment without much benefit. She came to our hospital where biopsy from lesions over elbow revealed dense inflammatory exudate, septate fungal hyphae showing acute angle branching on H and E stain and PAS stain, which is suggestive of aspergillosis. Scrapping from oral lesion also revealed inflammatory cells with septate fungal hyphae with acute angle branching on PAP stain. Histopathological, cytological study and fungal culture show fungal infection caused by Aspergillus niger. In cutaneous aspergillosis, surgical excision alone or combination with drug therapy was found to be curative. The present case report was important due to its rarity.

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Section: Discussionsupporting

confidence: 86%

Cutaneous aspergillosis in an immunocompetent patient: a case report

Bagate

Birare

Jadhav

et al. 2020

Trop J Pathol Microbiol

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“…Aspergillosis is an uncommon opportunistic fungal infection caused by a variety of species of which A fumigatus and A niger are the common ones. 22 In some cases, diagnosis of cutaneous aspergillosis can be made immediately by examining a potassium hydroxide preparation from the imprint material of biopsy specimens. Cytology reveals spores, multiple septate hyphae with 458 branching, and/or Aspergillus heads.…”

Section: Discussionmentioning

confidence: 99%

More experiences with the Tzanck smear test: Cytologic findings in cutaneous granulomatous disorders

Durdu

Baba

Seckın

2009

Journal of the American Academy of Dermatology

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“…Primary cutaneous aspergillosis (PCA) is an unusual opportunistic fungal infection mostly occurs in patients with malignancies, diabetes, trauma or on long-term corticosteroids 1 2. Aspergillus is ubiquitous; it can be found in water, soil and organic debris.…”

Section: Introductionmentioning

confidence: 99%

Primary cutaneousAspergillus fumigatusinfection in immunocompetent host

et al. 2020

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Primary cutaneous aspergillosis (PCA) occurs through inoculation of fungal spores directly into the skin from the environment through disrupted skin such as in burns, surgery or penetrating trauma patients. Most cases reported in literature were in the immunocompromised, rarely in immunocompetent patients. The characteristic lesion of cutaneous aspergillosis is a black eschar on a red plaque, or nodule at the site of skin injury. The diagnosis of PCA can be made by identifying hyphal forms on routine H&E staining or special stains such as periodic acid-Schiff or Gomori methenamine-silver stains on skin biopsy and by fungal cultures. We report a case of an 80-year-old farmer who developed cutaneous aspergillosis after a surgical procedure without any systemic spread. The diagnosis was made by histopathology and tissue fungal cultures. He was treated with incision and drainage followed by oral voriconazole for 4 weeks; which led to clinical recovery.

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Primary cutaneous aspergillosis

Cited by 13 publications

References 3 publications

Cutaneous aspergillosis in an immunocompetent patient: a case report

Cutaneous aspergillosis in an immunocompetent patient: a case report

More experiences with the Tzanck smear test: Cytologic findings in cutaneous granulomatous disorders

Primary cutaneousAspergillus fumigatusinfection in immunocompetent host

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