Primary Choroid Plexus Papilloma of the Cauda Equina. A Case Report

DeMarchi, Ryan; Khalidi, Hisham Al; Fazl, Mahmood; Bilbao, Juan M.

doi:10.1017/s0317167100010386

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…CPPs that arise outside of the ventricular system are very rare and may occur due to the enlargement of an intraventricular papilloma or drop metastasis along the cerebrospinal fluid pathways from a primary intracranial CPP or develop from ectopic foci of the choroid plexus [ 12 , 13 ]. Sporadic literature reviews describing primary intraspinal cord CPPs have reported occurrence at the sacral nerve roots, sacral canal, or cauda equina [ 10 , 14 , 15 ]. Because these CPP locations are extremely rare, they are often initially approached as common primary tumors of the spinal cord.…”

Section: Discussionmentioning

confidence: 99%

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A case report of atypical choroid plexus papilloma in the cervicothoracic spinal cord

Hiền

Duc

et al. 2022

Radiology Case Reports

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Choroid plexus papillomas (CPPs) are uncommon, benign intracranial tumors that can occur in both children and adults. In adults, CPPs are typically identified in the fourth ventricle, whereas in children, they most commonly occur in the lateral ventricle. CPPs that arise from the extraventricular system are extremely rare and difficult to diagnose. We report a case of extraventricular, atypical CPP located in the cervicothoracic spinal cord of a 2-year-old girl.

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Section: Discussionmentioning

confidence: 99%

“…DeMarchi et al. [14] described a case of CPP arising from cauda equina, with a differential diagnosis that included meningioma, neurofibromatosis, schwannoma, and ependymoma.…”

Section: Discussionmentioning

confidence: 99%

A case report of atypical choroid plexus papilloma in the cervicothoracic spinal cord

Hiền

Duc

et al. 2022

Radiology Case Reports

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Imaging findings of extraventricular choroid plexus papillomas: A study of 10 cases

Shi

Chen

et al. 2016

Oncology Letters

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Abstract. Extraventricular choroid plexus papillomas (CPPs) are rare. In this study, we reveal the imaging findings of CPPs located in extraventricular sites. The imaging findings of 11 masses [10 masses on magnetic resonance imaging (MRI) and one mass on computed tomography (CT)] of extraventricular CPP in 10 patients were retrospectively observed. The mass site, size, contour, signal intensity, cystic or solid appearance, calcification, capsules, degree and pattern of enhancement, and hydrocephalus were evaluated based on CT or MRI. The misdiagnosis rate of CPPs in extraventricular sites was 80.0% (8/10). Solitary masses and multiple masses were observed in nine patients (90.0%, 9/10) and one patient (10%, 1/10), respectively. In addition to the typical imaging findings [a lobulated, cauliflower-like or mulberry-like mass that is homogeneous isointense or slightly hypointense on T1-weighted imaging (T1WI) and heterogeneous isointense or slightly hyperintense on T2WI], four masses had round or oval contours and three had cystic components; abnormal signal intensity (mixed hyperintense signals on T1WI and T2WI or slightly hyperintense signals on T1WI or hypo-/hyperintense on T2WI) and low or no enhancements were observed in three and six masses, respectively; absence of hydrocephalus and mild or local hydrocephalus were each observed in four subjects, respectively. Hemorrhage and psammomatous bodies and/or calcification were observed in four and three masses, respectively. In conclusion, in addition to the typical imaging findings, atypical imaging findings, including atypical contours, abnormal signal intensity, low enhancement and absence of hydrocephalus were also observed in extraventricular CPPs.

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Atypical Choroid Plexus Tumor of the Cauda Equina With Metastases to the Spinal Cord and Brain

Rizvi,

Hussein,

Quezado

et al. 2024

Cureus

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We report a case of a 57-year-old man with a tumor arising from the cauda equina with spinal cord and intracranial metastases in the basal cisterns and along the cranial nerves. He presented with severe lower back pain and mild gait imbalance. His imaging revealed a large mass in the lumbosacral region with involvement of the cauda equina, intradural extramedullary enhancing metastases in the thoracic spinal canal, and intracranial metastases in the suprasellar cistern and along both trigeminal and facial/vestibulocochlear nerve complexes. Pathological examination of the resected thoracic spinal cord mass showed an atypical papillary proliferation with moderate nuclear pleomorphism and rare mitotic figures. While the morphologic and immunophenotypic features were consistent with the diagnosis of a choroid plexus tumor, the atypical location for this entity required the exclusion of other epithelioid tumors with papillary architecture. Additional immunohistochemical markers were used to exclude a metastatic adenocarcinoma, a papillary variant of a meningioma, and a papillary variant of an ependymoma. Ultimately, methylation-based tumor profiling determined that the methylation class was a match for "plexus tumor" resulting in the integrated diagnosis of the tumor with features of choroid plexus papilloma. This is a unique presentation for both the location and the metastatic spread. The methylation profile was instrumental in establishing this diagnosis.

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Primary Choroid Plexus Papilloma of the Cauda Equina. A Case Report

Cited by 3 publications

References 16 publications

A case report of atypical choroid plexus papilloma in the cervicothoracic spinal cord

A case report of atypical choroid plexus papilloma in the cervicothoracic spinal cord

Imaging findings of extraventricular choroid plexus papillomas: A study of 10 cases

Atypical Choroid Plexus Tumor of the Cauda Equina With Metastases to the Spinal Cord and Brain

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